Many new pharmaceuticals are based on large biomolecules like proteins. Even small differences in the protein structure can cause significant changes in the efficacy and safety of these drugs. Furthermore, these large molecules are difficult to characterize without advanced instrumentation and methods. Current technologies still struggle with robustness and reproducibility. This study aims to introduce […]

Many new pharmaceuticals are based on large biomolecules like proteins. Even small differences in the protein structure can cause significant changes in the efficacy and safety of these drugs. Furthermore, these large molecules are difficult to characterize without advanced instrumentation and methods. Current technologies still struggle with robustness and reproducibility. This study aims to introduce […]

Pharmacotherapy is one of the primary treatments for psychiatric disorders. Given the variation in individual response, and the current trial-and-error treatment, a more personalized approach is needed. The Mitacs Elevate postdoctoral trainee will gain direct experience with all aspects of using pharmacogenetic testing to personalize medication prescriptions for patients, and the commercialization of the test. […]

Pharmacotherapy is one of the primary treatments for psychiatric disorders. Given the variation in individual response, and the current trial-and-error treatment, a more personalized approach is needed. The Mitacs Elevate postdoctoral fellow project involves the use of pharmacogenetic testing to personalize medication prescriptions for patients, and the commercialization of pharmacogenetic testing. A main component of […]

The main contribution by the interns will be to function as a research assistant to help with the labour intensive laboratory experiments, data analysis, and reporting tasks. The students will have a chance to work with the engineering staff at CHI and will provide additional support during the study.

Drug resistance of medically relevant microorganisms poses a grave threat to human health and has severe economic consequences. Fungal pathogens pose an additional complication as they are closely related to their human host. Current therapies to treat fungal infections are limited and drug resistance has already emerged in the clinic. We have conducted extensive research […]

Global population growth, urbanization and changing climate patterns have increased the demand for potable water, wastewater reuse and value recovery from wastewater, and treatment of industrial process water. Population growth also results in increased demand for the shipping of goods by ocean freight, with the associated risk of the transport of unwanted marine life from […]

Global population growth, urbanization and changing climate patterns have increased the demand for potable water, wastewater reuse and value recovery from wastewater, and treatment of industrial process water. Population growth also results in increased demand for the shipping of goods by ocean freight, with the associated risk of the transport of unwanted marine life from […]

The Ontario government provides healthcare funding to fourteen Local Health Integration Networks (LHINs) across Ontario. LHINs in turn are responsible for structuring health care delivery and allocating funds to best meet the needs of the population in the region. However, there are limited tools available to help LHINs evaluate the system-wide implications of proposed policy […]

The UbiLab and the CSA Group are collaborating on the development of a roadmap for a data integration infrastructure that will enable Ambient Assisted Living technology to share data at a wider scale. The current technology landscape has resulted in manufacturers of Internet of Things and Ambient Assisted Living technologies generating siloed data that provide […]

Knowledge workers (i.e., researchers, business consultants and analysts, research-program managers) produce documents (research publications, analysis reports, opinion pieces, calls-for-proposals, and blog posts) through which they express their knowledge and opinions. They also read and review similar documents, produced by individuals and organizations in their domain of interest and expertise, to keep current with their domain. […]

Helicobacter pylori is a bacterium that causes 65% of gastric ulcers and cancers worldwide. Current snit- H. pylori treatments often fail because the bacteria have become resistant and they have serious side effects. We are looking into using molecules produced by bacteria called lactobacilli that are a natural component of the human gastro-intestinal flora to […]