Immunotoxins (ITs) are representing a subset of antibody drug conjugates where the synthetic toxin is replaced by a bacterial protein toxin. Major drawback is related to the immunogenicity of the protein not allowing repeated application. Consequently targeted human cytolytic fusion proteins (hCFPs) have been developed to replace the foreign protein toxin by a human apoptosis […]

Surfactants are chemical compounds used as active ingredients in a large array of products, such as soaps and detergents. However, they can become pollutants and toxicants, and their production is not sustainable (derived from petrochemical processes). One attractive alternative is the use of biological surfactants from microbial origin. We have identified a promising new biosurfactants […]

In the context of an aging population, it is becoming more and more important to develop novel innovative kinds of sensors, able to detect early health changes that could potentially affect people’s health. Within this Globalink Research project, we intent to develop plasmonic based sensors, small, cheap and easy to deploy, which will be used […]

This project aims to develop a novel therapeutic drug aimed at revolutionizing the treatment of severe cardiovascular diseases (CVD) and sepsis. Our project focuses on the modification of the ADAMTS13 protein, an enzyme that plays a crucial role in the blood clotting process. In patients with severe CVD or sepsis, ADAMTS13 is rapidly degraded, leading […]

Wearable non-invasive devices have emerged as useful tools for tracking physiological data from companion animals. By combining this data with machine learning techniques, it is possible to proactively detect disorders and prompt owners to seek medical attention. This research aims to asses the efficacy of this approach by using wearable devices for continuous monitoring and […]

Our project focuses on developing a bioprinting technology for treating severe burns. We aim to reduce scarring and enhance skin regeneration, which can significantly improve the lives of burn victims. This technology has the potential to make a big difference in the medical field, but it’s a challenging journey, especially due to the strict regulations […]

Urinary tract infections (UTIs) are one of the most common bacterial infections globally, affecting millions of people each year. The inappropriate use of antibiotics for UTIs is a significant driver of antibiotic resistance, posing a grave threat to public health. Complicated UTIs, characterized by treatment failure, recurrent infections, and increased mortality, disproportionately affect vulnerable populations, […]

In this project, the team will build a strong business foundation for a startup vehicle ‘Neuropeutics Inc’ to conduct further R&D and commercialize a new effective treatment for neurodegenerative diseases, namely ALS and FTD. That is, the team will develop a sustainable business model, a financial budget, a funds raising plan and marketing material. The […]

NorthMiRs is developing nanotechnology-enabled gene therapies for the treatment of sepsis. We have determined microRNAs that are dysregulated in septic patients and packaged them into a stable, synthetic, and scalable lipid nanoparticle delivery vehicle. Our lead therapeutic, NM-001, a miRNA replacement therapy for sepsis-associated cardiomyopathy has been shown to be anti-inflammatory, anti-microbial and protects organs […]

EPAID Technology: EPilepsy AI-Driven Technology aims to automate electrophysiological signal processing practice to assist clinicians in the treatment of epilepsy. We will partner with Springboard, who provides strategically positioned resources to Atlantic Canadian universities and colleges alike, helping them transfer both knowledge and technology into the private sector.

Myelofibrosis is a chronic and life-threatening blood disease. There is a need for accurate risk stratification approaches to guide personalized medicine decisions for these patients. To address this need, we developed a non-invasive blood-based test that is cost-effective, scalable and accurate. Through the Lab2Market program we will explore the market and develop the business case […]

We will assess the quality and suitability of blood and blood-derived products using a fast and economical approach that combines measurements of molecules in the blood product identified by their weight and computational approaches to make sense of all the data generated. Normal blood products have thousands of small molecules in common. By monitoring a […]