Triple negative breast cancer (TNBC) is a highly invasive and heterogenous disease that does not express oestrogen receptor and progesterone as well as the human epidermal growth factor receptor-2 and accounts for approximately 20% of all breast tumors. Its heterogenicity makes unlikely to reach the complete TNBC patient population with a single therapeutic agent. Therefore, […]

The major problem with intervention for schizophrenia is the inability to treat all symptom categories (positive, negative, and cognitive) sufficiently. The need to test new novel therapies is crucial, which may prevent the onset of this debilitating disorder. Since intervention is limited to individuals at high risk, researchers have turned to animal models to test […]

ace à la propagation alarmante des bactéries résistantes aux antibiotiques, le développement de nouveaux antimicrobiens avec des modes d’action innovateurs est devenu une priorité mondiale. Parmi les différentes alternatives, les peptides antimicrobiens d’origine bactérienne comme les bactériocines sont très prometteurs. Ce projet s’intéresse particulièrement à cinq bactériocines produites par la bactérie Lacticaseibacillus paracasei qui ont […]

Cancer is associated with an accumulation of alterations in genes that confer the ability of cancer cells to grow uncontrollably. These alterations can contribute to increased deleterious function or loss of function of genes that normally regulate cell growth. Genes in our cells are organized on chromosomes which duplicate every time a cell divides. In […]

Immunotoxins (ITs) are representing a subset of antibody drug conjugates where the synthetic toxin is replaced by a bacterial protein toxin. Major drawback is related to the immunogenicity of the protein not allowing repeated application. Consequently targeted human cytolytic fusion proteins (hCFPs) have been developed to replace the foreign protein toxin by a human apoptosis […]

Surfactants are chemical compounds used as active ingredients in a large array of products, such as soaps and detergents. However, they can become pollutants and toxicants, and their production is not sustainable (derived from petrochemical processes). One attractive alternative is the use of biological surfactants from microbial origin. We have identified a promising new biosurfactants […]

In the context of an aging population, it is becoming more and more important to develop novel innovative kinds of sensors, able to detect early health changes that could potentially affect people’s health. Within this Globalink Research project, we intent to develop plasmonic based sensors, small, cheap and easy to deploy, which will be used […]

This project aims to develop a novel therapeutic drug aimed at revolutionizing the treatment of severe cardiovascular diseases (CVD) and sepsis. Our project focuses on the modification of the ADAMTS13 protein, an enzyme that plays a crucial role in the blood clotting process. In patients with severe CVD or sepsis, ADAMTS13 is rapidly degraded, leading […]

Wearable non-invasive devices have emerged as useful tools for tracking physiological data from companion animals. By combining this data with machine learning techniques, it is possible to proactively detect disorders and prompt owners to seek medical attention. This research aims to asses the efficacy of this approach by using wearable devices for continuous monitoring and […]

Our project focuses on developing a bioprinting technology for treating severe burns. We aim to reduce scarring and enhance skin regeneration, which can significantly improve the lives of burn victims. This technology has the potential to make a big difference in the medical field, but it’s a challenging journey, especially due to the strict regulations […]

Urinary tract infections (UTIs) are one of the most common bacterial infections globally, affecting millions of people each year. The inappropriate use of antibiotics for UTIs is a significant driver of antibiotic resistance, posing a grave threat to public health. Complicated UTIs, characterized by treatment failure, recurrent infections, and increased mortality, disproportionately affect vulnerable populations, […]

In this project, the team will build a strong business foundation for a startup vehicle ‘Neuropeutics Inc’ to conduct further R&D and commercialize a new effective treatment for neurodegenerative diseases, namely ALS and FTD. That is, the team will develop a sustainable business model, a financial budget, a funds raising plan and marketing material. The […]