Background- Bacterial analysis in the field is complex and often imprecise. It is therefore difficult to detect and identify a specific strain in a timely manner, which complicates the choice of an optimal treatment regimen. This is a critical issue and bacterial infection are taking an increasing toll on the population and the health services. […]

The discovery of CRISPR-based gene therapy methods using viral vectors, and SARS-CoV-2 vaccines based on lipid nanoparticle formulations has revolutionized the field of personalized medicine, and promises revolutionary applications for curing cancer, genetic disorders, and other diseases on the molecular level. To facilitate the validation of new therapies, biopharma companies use analytical ultra-centrifugation (AUC) to […]

Bio-Brick Labs manufactures concrete and natural stone replacements for veneers and rainscreen applications. The material is made of 85% recycled material, captures CO2, and requires no heat, high-energy machinery, or exotic materials to make. This results in a carbon-negative product during the lifespan of the material. This project aims to evaluate the in-service performance of […]

The proposed research aims to apply the capabilities of machine learning to study molecular models of cell membranes. Cell membranes are composed of fluid lipid bilayers with a highly dynamic nature. By developing neural network models for the simulation of lipid bilayers, we seek to overcome the shortcomings of current computational methods, providing superior accuracy […]

Heart disease bears a heavy burden on the health care system. Curative approaches are extremely limited and surgery is often the best course of treatment. Heart disease encompasses a variety of disorders, but among these, myocardial infarction (MI), or a heart attack, presents an especially difficult case for treatment. MI is caused by destruction of […]

Currently, over 95% of new anti-cancer drugs fail during clinical trials (1). Despite significant technological advances, drug development has become slower and more expensive. The root cause is that current preclinical cancer models, such as 2D cell layers and animal models, fail to accurately recreate human biology. This makes it very difficult to predict how […]

Diagnostics are critical to our healthcare infrastructure, with substantial impacts on patient care and public health policy. Proteins have been used as diagnostic markers for disease monitoring for nearly 200 years, however, current analytical methods require expensive equipment and expert technicians. This restricts the use of such methods to centralized laboratories where they process samples […]

Treatments for neurodegenerative disorders represent an unmet medical need, affecting more than 50 million people worldwide. Through extensive research, we have identified two innovative therapeutic targets that have demonstrated promising effects in enhancing the regeneration and resilience capacities of neurons in animal models of Amyotrophic lateral sclerosis and Huntington’s disease. Our approach not only has […]

Phytopathogenic fungi secrete diverse enzymes to help them infect host plants. Foliar phytopathogens like Colletotrichum species, contain tandem copper radical oxidase (CRO) and peroxidase genes. The CRO-peroxidase pair is co-secreted during initial leaf penetration phases. The CRO oxidizes long-chain alcohols found in the leaf cuticle while the peroxidase activates the CRO. We discovered that the […]

The challenges posed by yield loss and plant diseases facing climate change are on the rise. And it is impossible to ignore fungal pathogens in agriculture. Sclerotinia sclerotiorum is one of the most devastating plant pathogens that can cause substantial damage to major crops such as canola, various beans, and sunflowers in Canada, the USA, […]

The proposed research project at the Turak Functional Nanomaterials Research group at Concordia aims to enhance the efficiency of solar energy data measurement and analysis from emerging solar cell technologies. In a world increasingly focused on sustainable energy sources, efficient utilization of solar power is paramount. The lab manages vast data, including complex images of […]

The proposed research project aims to investigate how Saccharomyces cerevisiae, a microorganism commonly used in the food and biofuel industry, responds to changes in temperature and manages to withstand high temperatures. Yeast cells face various types of stress as the environment conditions change, both in natural situations and during industrial processes. S. cerevisiae has developed […]