Functional MRI for post-stroke rehabilitation

Motor impairment is a common symptom after stroke and recovery of motor function is important for regaining the patient’s independence in activities of daily living. Being able to predict motion recovery and outcomes soon after stroke could support clinicians, patients and families to set proper goals for rehabilitation and appropriate plans of time and resource […]

Read More
L2M – Revolutionizing Cell Culture: Advanced Collection and Extraction Kits for Enhanced Reproducibility and Efficiency

The proposed project aims to develop innovative cell culture collection and extraction kits designed to streamline and improve the process of collecting cell samples in research laboratories. By addressing the current challenges of manual sample collection, such as time consumption, variability, and error-prone methods, our kit will enhance the reliability and efficiency of biological and […]

Read More
Computational Modeling of Fluid-Structure-Chemical Interactions in Fish Swimming

Aquatic species, such as fish use effective methods for navigation and propulsion in marine environments. Understanding these functionalities of detecting predators, preys, food, and mates by sensing changes in water velocity and pressure offer valuable insights to design efficient underwater robots. Although underwater odor and chemical cues are crucial for fish navigation, the exact mechanisms […]

Read More
Advancing Therapeutic Nanotechnologies: Quantitative Insights into mRNA-Lipid Nanoparticles

Leveraging the groundbreaking research of Dr. Sabrina Leslie and her team, this project represents a significant stride towards mastering the analysis of mRNA within Lipid Nanoparticles (LNP). Building upon our novel findings, published in ACS Nano (2021), which introduced the first quantitative imaging technique for RNA-LNP formulations, we aim to precisely quantify mRNA molecules in […]

Read More
Antiviral Activity of the Proprietary Samples

Blue-O Technology Inc has developed proprietary samples that have demonstrated antiviral activity against HIV-1 and influenza. Blue-O Technology Inc has purified these proprietary samples to isolate different subunit components. These subunit components will be used by the intern determine which components have anti-HIV or anti-influenza activity. Initial experiments will be undertaken in cell culture systems […]

Read More
Development of a generative adversarial neural network for synthetic data generation to enhance AI-based OCT image analysis.

In the development of AI-assisted imaging tools, Perimeter faces the challenge of enhancing the accuracy and efficiency of tumor margin assessments. This research investigates whether generative AI can be used to synthesize supplemental data, alongside automated data annotation techniques can drive measurable improvements in the performance of Perimeter’s AI tools.

Read More
Proteomic Analysis of Microbial Communities for Enhanced Bioremediation of BTEX Contaminated Sites

Soil and groundwater pollution with harmful petroleum contaminants such as BTEX is a global concern. BTEX has carcinogenic and mutagenic properties, therefore, it is essential to remove such contaminants for a healthy ecosystem. Microorganism-mediated bioremediation is an extremely promising technique that is cost-effective, efficient, and safe for the environment. However, limited biological knowledge about the […]

Read More
How spatial organization can promote the formation of complex objects

This research project, to be undertaken during a 4-month internship at Arizona State University, aims to develop an artificial chemistry system to investigate the influence of pore system topology on molecular complexity, using Assembly Theory as a measure. The project’s significance lies in its potential to enhance our understanding of Assembly Theory, with implications for […]

Read More
Enhanced AI Decision Support Module

AI Decision Support Module: An enhanced AI Decision Support Module aimed at streamlining the surgical review process through the identification of suspicious excision margins within medical imaging. Building upon an existing AI framework, which utilizes labeled data for the identification of potentially problematic regions, this project seeks to improve the model’s accuracy and reliability. The […]

Read More
Pharmacology of GBA1 Chaperones

Mutations in the enzyme glucocerebrosidase (GBA1) are the most common genetic risk factor for development of Parkinson’s disease (PD). PD is characterized by the buildup of abnormal protein deposits in the brain, followed by progressive loss of neurons and behavioural symptoms. Numerous studies have noted a correlation between reduced GBA1 activity and increased levels of […]

Read More
Drug Delivery Vehicle for Gene Silencing in the Posterior Segment of the Eye

Retinal diseases, such as age-related macular degeneration (AMD), cause vision blur and distortion, eventually leading to vision loss. AMD is the leading cause of blindness in patients over 60, affecting an estimated 200 million people worldwide. Current treatments require patients to receive monthly injections into the back of the eye, risking adverse effects and placing […]

Read More