L2M-Free Flow Counterflow Gradient Focusing

Our project focuses on improving protein purification using a novel continuous separation method; Free-Flow Counterflow Gradient Focusing (FF-CGF). Traditional purification methods are slow, inefficient, and result in high sample loss, making it difficult for industries like pharmaceuticals and biotech to recover valuable proteins. Our technology offers a faster, more efficient alternative without the need for […]

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L2M – Wonder Guard: An Integrated Catheter Bag Module with Electrochemical Biosensing and Machine Learning for UTI Detection

Wonder Guard is an advanced catheter bag system that uses electrochemical biosensors and machine learning to detect urinary tract infections (UTIs). The device is a module add-on to existing hospital catheter systems that can continuously produce and analyze data to monitor UTIs, with faster results than standard urine cultures and richer insights than urine dipsticks. […]

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L2M – Probes to Enable Imaging Small Molecules in Cells

Cellular imaging enables the study of diseases in myriad ways, consequently impacting human health. Through visualizing individual cells, clinicians are able to diagnose diseases and scientists are able to develop drugs to treat them. There are many powerful tools to visualize cells, including fluorescence and electron microscopy. However current common imaging techniques fall short for […]

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L2M QC Spring 2025 | A High-Throughput Platform for Ribomodule Selection and Optimization in Therapeutic RNA

This project aims to assess the market potential of a platform for producing ribomodules, specialized RNA fragments designed to enhance the stability, expression control, and functionality of therapeutic RNA (ARNth). The platform leverages high-throughput screening to develop tailored ribomodules that regulate gene expression and improve RNA stability through optimized circularization. While these innovations hold great […]

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L2M QC Spring 2025 | Biosynthèse innovante de CBD (Cannabidiol) : Production durable à partir de microalgues génétiquement optimisées

Nous proposons une solution innovante et respectueuse de l’environnement pour produire du Cannabidiol (CBD), une molécule reconnue pour ses nombreuses applications thérapeutiques. Aujourd’hui, la production de CBD repose principalement sur la culture de la plante de cannabis et sur des procédés d’extraction chimique, des méthodes coûteuses, gourmandes en ressources naturelles et parfois polluantes. Grâce à […]

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L2M QC Spring 2025 | Sparx Genomics

Leveraging large-scale genetic data for identifying novel therapeutic targets. Developing a new drug takes an average of twelve years and costs over a billion dollars. This exorbitant cost is largely due to the high failure rate in drug development. In fact, more than 90% of drugs tested in humans will never reach the market. In […]

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L2M QC Spring 2025 | Recapitulating the Tumor Immune Microenvironment and Stromal Interactions with Customizable Living 3D Bioprinted Human Solid Tumor Models for High-Throughput Preclinical Oncology and Translational Drug Development

We are developing a library/biobank of in vitro 3D bioprinted living tumor models to accelerate cancer drug development and bridge the translational gap. By incorporating human cells into organ-specific proprietary 3D bioprintable hydrogels we replicate the biochemical and physical properties of the tumor microenvironment with a high degree of complexity using only bio-derived materials. By […]

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Nutrient Recovery of Spent Biomass and Lipid-Extraction from Wastewater in the Production of Thraustochytrids

This project aims to explore the novel concept of nutrient recycling within the production process of microalgae biomass for biofuels and bioproducts. After extraction of primary products, the remaining waste materials which contain potential nutritional value will be evaluated for potential recycling as feedstocks into the production of additional microalgae biomass. Completion of this project […]

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Globalink Research Award Application – Internship in Switzerland (May 1 2025 start) – McKinley Van Klei

Standard medical imaging techniques used to diagnose and inform treatment of spinal conditions include X-Ray, computed tomography (CT), and magnetic resonance imaging (MRI). These images neglect to capture the in vivo dynamic behavior of the spine during activities of daily living, since patients remain as still as possible to capture clear image. In 2023, 20% […]

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Understanding the chemistry of cancer with a smart paper chip

The purpose of the project is to design a paper-based device for the co-detection of nitric oxide (NO) and glucose in a tumor angiogenesis model. By combining paper technologies to electrochemical sensing, we envision that an easy-to-use, smart tumor model can be built. The devices will be tested on co-cultured endothelial and tumor cells, to […]

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Non-invasive estimation of continuous arterial blood pressure using data from a wearable multi-sensor device.

Cardiovascular diseases are the leading cause of death worldwide, yet long-term continuous blood pressure monitoring, an accurate technique for prevention and early detection, remains largely unavailable outside of clinical settings. Such measurements presently require invasive, expensive, and impractical instrumentation thus preventing widespread use in non-clinical settings like at home and in research. This project aims […]

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Developing a dichromatically-gated light-inducible transcription factor for spatiotemporal control of gene expression in 3D cellular architectures

Light can be used to control biological processes in living cells, a technique called optogenetics. Originally developed to control neural activity, optogenetics has been expanded to control protein interactions and gene expression with a high degree of spatial and temporal control. This has opened exciting possibilities in developmental biology and tissue engineering. However, current optogenetic […]

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