Lyme disease is a tick-borne infection caused by the bacteria Borrelia burgdorferi. It requires early detection for effective antibiotic treatment. Unfortunately, Lyme disease is hard to diagnose, and current tests require trained scientists, specialized lab settings, and expensive equipment. Here, the project aims to develop a quick, low-cost, and user-friendly test for Lyme disease that […]

Receptor proteins are important for therapeutics, medicines, diagnostics and biomanufacturing. Generating new proteins is incredibly difficult however machine learning techniques have been developed to assist in evolving proteins. Using these techniques, I plan to create receptor mimics that are smaller and have improved properties. These will benefit many industries such as therapeutics, medicines, diagnostics and […]

G-quadruplex (G4) are a type of DNA or RNA that can fold into different types of structures, where four guanine bases are held together by Hoosteen hydrogen bonds. The type of structure that forms plays a key role in genomic events that can affect telomerase activity. Unregulated, telomerase can cause tumour formation, and in some […]

De nombreuses pathologies et troubles dégénératifs sont caractérisés par l’accumulation de dépôts protéiques fibrillaires. Ces fibres amyloïdes se retrouvent dans plusieurs maladies, dont la maladie de Parkinson, d’Alzheimer et le diabète de type 2. Plusieurs mécanismes cellulaires contribuent aux voies cytotoxiques de ces protéines amyloïdogéniques, notamment la perturbation des membranes cellulaires. Le mécanisme de perturbation […]

Le projet de recherche se concentre sur l’utilisation d’exosquelettes dans le secteur manufacturier, où les travailleurs effectuent des tâches physiquement exigeantes pouvant entraîner des troubles musculo-squelettiques (TMS). L’objectif est d’évaluer l’impact du Muscle Suit Every, un exosquelette portable, sur la réduction de la fatigue musculaire et de la charge cognitive des travailleurs. La recherche sera […]

Friedreich is an hereditary disease, which in due to a mutation of the frataxin gene. This mutation leads to a reduced production of the frataxin protein. This leads to oxidative stress and death of the cells. The death of the neurons and cardiomyocytes are responsible for progressive severe neurological and cardiac symptoms. The aim of […]

Overcoming an injury as an athlete is not easy and usually requires the help of professionals to guide the rehabilitation process. Athletic therapists, doctors and other health professionals in sports medicine are interested in better ways to help players get back to the game safely. Instead of following set rehabilitation protocols, we are now focusing […]

Species are delimited by barriers to reproduction, which can be caused by genetic incompatibilities that arise when isolated populations become two distinct species. Nevertheless, hybridization can occur when species are genetically similar enough to have few barriers to reproduction. If the hybrid offspring is viable and fertile, it can mate with either of the parental […]

Les tissus (peau, gencive, etc.) humains sont très importants assurant la protection du corps contre de multiples agents exogènes (produit chimique, microbes, pollution, etc.). Malheureusement, ces tissus sont fragiles et peuvent être la cible de multiples pathologies causant des réactions inflammatoires. Les principales maladies des tissus (peau et muqueuse buccale) sont fréquemment associées à une […]

La gastro-entérite chez les humains est souvent causée par Campylobacter jejuni, une bactérie microaérophile Gram négative. En raison d’une forte charge de Campylobacter dans les intestins des poulets, atteignant jusqu’à 10? UFC/g, la campylobactériose est principalement attribuée à la consommation et à la manipulation de produits de volaille contaminés tels que différentes découpes de viande […]

Aerated lagoons (ALs) are popular wastewater treatment systems in Quebec for their simplicity and cost-effectiveness. In 2014, Bionest Technologies introduced the KAMAK™ system, which uses fixed bacterial support technology to boost biofilm growth in ALs. Implemented at the Grandes-Piles AL, the KAMAK™ system enhances nitrification, increases biomass concentration, and reduces effluent total suspended solids (TSS). […]

We propose to investigate the physiological and ecological factors driving the loss of photosynthesis in green algae and their transition to a permanent heterotrophic lifestyle. Autotrophs produce organic molecules (such as carbohydrates) from inorganic compounds (CO2), and photoautotrophs are reliant on sunlight to do this. Photoautotrophs are the primary producers of most ecosystems. Most of […]