Intrafibrillar vs surface mineralization in bovine flexor tendon-derived collagen fibrils – an in vitro model of calcific tendinopathy of the human Achilles.

Calcific tendinopathy (CT) is a staged, reactive process where pre-calcific changes are followed by a calcific phase (formative, resting, resorptive) and by post-calcific remodelling in which hydroxyapatite-like deposits form and quite often resorb spontaneously. CT is most prevalent in the neck, foot and hip and within the foot. The Achilles is a well-documented site of […]

Read More
L2M Validate – Pi16 Therapeutics

The mission of PI16 Therapeutics is to improve skin health for the ~4 million Canadian’s suffering from long-term skin diseases, including clinically dry skin, chronic wounds, and severe burns. PI16 Therapeutics aims to produce skin solutions for these individuals by genetically engineering naturally occurring stem-cell like fibroblasts that express the gene Peptidase Inhibitor 16 (Pi16) […]

Read More
L2M – Bacterial Amplicon Tick Test (BATT)

Tick-borne diseases, including Lyme disease and Anaplasmosis, are an increasing public health concern in Canada, with rising case numbers driven by climate change and expanding tick populations. Current testing methods are limited as they typically detect only one pathogen at a time and often miss early-stage infections. As a result, many Canadians can go undiagnosed […]

Read More
Enhancement of a Pharmacogenomic Treatment Decision Support Tool for Schizophrenia

The GeneSight (GS) Psychotropic Test (AssureRx Health, Inc.) measures individual variations in drug-related genes and recommends optimal drug choices for individual patients. A clinical study will be conducted to validate novel gene markers of antipsychotic-induced weight gain for use in an enhanced version of GS. Sarah Groleau will be responsible for genotyping DNA from 600 […]

Read More
Enhancement of a Pharmacogenomic Treatment Decision Support Tool for Schizophrenia – Year two

The GeneSight (GS) Psychotropic Test (AssureRx Health, Inc.) measures individual variations in drug-related genes and recommends optimal drug choices for individual patients. A clinical study will be conducted to validate novel gene markers of antipsychotic-induced weight gain for use in an enhanced version of GS. Sarah Groleau will be responsible for genotyping DNA from 600 […]

Read More
L2M – Lumos Smart Light Therapy Glasses for Sleep and Mental Wellness Commercialization

This project will help an intern develop Lumos, a made-in-Canada light therapy glasses venture that aims to improve sleep and alertness. With support from the Lab2Market program, the intern will gain practical experience in identifying target users, developing a go-to-market strategy, and collecting early product feedback. Lab2Market will provide mentorship, training, and access to a […]

Read More
L2M Launch / Qc Fall 2025 / Espoir Biosciences

Ce projet vise à transformer une découverte scientifique prometteuse en une entreprise biotechnologique dédiée au développement d’un traitement innovant contre la sclérose latérale amyotrophique (SLA), une maladie neurodégénérative incurable. Issu du laboratoire du Dr Alex Parker au CRCHUM, le traitement proposé repose sur un mécanisme inédit de régénération des neurones endommagés. Les traitements actuellement disponibles […]

Read More
L2M – Health Validate – A Rapid and Portable DNAzyme-Based Biosensor for Early Colorectal Cancer Detection

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in Canada, with over 24,000 new cases and 9,300 deaths reported in 2023. Early detection significantly improves survival rates, yet current screening methods, such as stool-based tests and colonoscopies, have major limitations. Fecal tests often produce false positives, leading to unnecessary and invasive colonoscopies, […]

Read More
L2M Validation / Qc Fall 2025 / DeepScript

This project will support the development of DeepScript, a software platform that helps researchers find promising small molecules for drug discovery without needing to run large and expensive screening campaigns. Instead of testing hundreds of thousands of compounds, DeepScript uses biological data and artificial intelligence to predict which existing compounds are most likely to work […]

Read More
L2M Validation / QC Automne 2025 / Next-Generation Paper Diagnostics: Point-of-Care Smart Detection of Infection

This project focuses on creating a low-cost, paper-based sensor that can quickly detect and archive Pseudomonas aeruginosa, a harmful bacterium found in both medical and environmental settings. This includes infections in hospitals and contamination in water systems—two areas where fast, accurate detection is essential for protecting public health. The sensor leverages smart electrochemical technology to […]

Read More
L2M Launch / Qc Fall 2025 / mTatt

mTatt is a medtech startup developing functional microtattoos for real-time, at-home health monitoring. Using dissolving microneedles — biocompatible structures under 1 mm in length — we painlessly deliver fluorescent sensors into the skin, creating a functional tattoo. These sensors respond to key biomarkers like NT-proBNP, glucose, or electrolytes, providing clinically valuable insights without blood draws […]

Read More