Optimizing hearing aids for speech intelligibility, sound quality and emotional speech

The lack of correspondence between the clinic setting and real world listening environments may explain, in part, why hearing instruments optimized in the clinic often result in poor adherence of hearing instruments in everyday life. To address the disconnect between communication in everyday listening situations where talkers often speak with emotion and audiology clinics where […]

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Biomolecular Structure Analysis to Accelerate Development of New Vaccines and Monoclonal Antibodies

Manufacturing of consistently high quality products is the commitment of pharmaceutical industry. To achieve this, new products must be thoroughly tested and the results meet government-approved product specifications. Improving existing and adopting improved analytical technologies for product testing ensure the production of safe and effective products. This is particularly critical for the manufacturing of biologic […]

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Development of an in planta soybean transformation method

This research project aims at establishing a cheap and simple alternative genetic transformation method for soybean termed in planta. Three in planta methods, named (i) tissue-culture independent callus and adventitious buds generation (TCICABG), (ii) sonication and in vivo selection/regeneration (SivSR) and (iii) in vitro embryonic axis sonication and direct regeneration (EAR), will be tested to […]

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Developing an electrochemical sensor using in-situ synthesis of a stand-alone MIP membrane for bacteria detection in water

In this project, a microfluidic sensor will be developed for bacteria detection in water. The microfluidic device enables in-situ synthesis of molecularly imprinted polymer (MIP) membranes with bacteria imprinted cavities. The sensor works based on bounding the target bacteria to the MIP membrane, thereby altering the electrochemical signal which will be measured using in-situ fabricated […]

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Développement et transfert technologique d’un procédé de biométhanisation hybride en voie humide/sèche pour valoriser des résidus de ferme agricoles et forestiers

Les changements climatiques causés par l’augmentation des émissions de gaz à effet de serre (GES) constituent l’un des plus grands enjeux environnementaux de notre époque. Le secteur de l’élevage contribue considérablement à ces émissions en gérant mal ses résidus. Dans ce contexte, Écoboeuf une entreprise de production bovine tend à améliorer la gestion des fumiers […]

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MRI Quantification for Predicting Post Stroke Motor Functions

Stroke is a leading cause of adult disability. Stroke results in neural damage to the brain and subsequent physical, cognitive, and affective impairments. Motor impairment after stroke is common and affects around 80% of patients. A primary concern immediately after stroke for patients, their relatives, and their caregivers is the prospect of recovery in the […]

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Developing a coupled enzyme cascade assay to screen PETase activity

This project aims at developing a coupled enzyme assay strategy that will allow us to engineer and screen engineered PETase enzymes that are useful in degrading otherwise non-biodegradable plastics. The proposed method will be faster and robust compared to existing assay methods. PolyTide Inc. aims to apply this technique towards engineering PETase enzymes it is […]

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ALBINOMICS: A comparative approach to studying the evolution and function of mycoheterotrophy in tribe Neottieae (Orchidaceae)

This study investigates the evolution of plant-fungal symbiotic relationships and trophic mode changes, with a focus on mycoheterotrophy, the ability to obtain fixed carbon from fungi. Mycoheterotrophy has evolved multiple times across various plant lineages. While most species perform both photosynthesis and mycoheterotrophy, several hundred species have completely quit photosynthesis and become fully mycoheterotrophic. These […]

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Electrically controlled 1-DOF forearm-hand active prosthesis for children

The essence of the project is to create an adaptive electrically controlled prosthesis for a child’s hand. The prosthesis should be able to be resized for the patient at the stage of computer-aided design. To realize this, it is proposed to create a parametric model of the prosthesis in a CAD system. Also, during the […]

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Exploring the function of the Pic2 protein in copper transport

Yeast will be used as a model to investigate inherited mitochondrial diseases in this research project, with a particular emphasis on the functional role of the Pic2 protein. Although initially identified as a mitochondrial phosphate transporter, recent studies have proposed its involvement in copper transport. To gain insight into Pic2 and its function, a combination […]

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Study the dynamics of changes in the nutritional value of wetlands for important waterfowl species after removing the invasive species Phragmites australis from the ecosystem in the Ramsar wetland and international birding area on the northern shore of Lake Ontario called Long Point

The availability of vegetative forage material is a crucial factor in determining the quality of habitat for waterfowl. During their migratory staging, waterfowl rely on consuming seeds and tubers of specific wetland plants to build their energy reserves. Phragmites australis, an invasive species, provides very little forage value, and is known to degrade wetland habitat […]

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