The TRAPP complex is a large protein complex involved in a number of different cellular processes including membrane traffic. Individuals with mutations in the genes encoding the proteins of this complex have been increasingly identified using whole exome and whole genome sequencing methods. To date, only a single individual with a candidate (and not yet […]

Parkinson’s disease (PD) is the second most common neurodegenerative disease. PD is caused by genetic predispositions leading to neuronal cell death. Dysfunction of damaged mitochondrial turnover by mitophagy (mitochondrial autophagy) and the ubiquitin-proteasome system has been found in most cases of genetic PD. The ubiquitin-proteasome system mediates protein degradation trough ubiquitination – a post-translational modification […]

Autism spectrum disorder (ASD) is characterized by social and communication impairments and by restricted and stereotyped behaviors. Sensory processing alterations seem to have an important toll in ASD individuals. In the present study, ASD and typically developing (TD) children between 8 and 12 years old will participate in a task involving visual and auditive integration […]

Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder characterized by social communication deficits, restricted interests and repetitive behaviours. Accumulating evidence suggests neuroimaging to have a great potential in clarifying the neurological bases of ASD. In this project we will use magnetoencephalography (MEG) to investigate the neuromagnetic mechanisms of information processing in typical and […]

Using genome-wide data in collaboration with the Peruvian Genome Diversity Project, our goals are: (i)Populations from the Peruvian Central Andes are highly homogeneous. We use Approximate Bayesian Computation and patterns of identity-by-descent to infer when the intensification of the gene pool homogenization on this geographic region started, in the historical context of the Andean prehistory. […]

The proposed research would examine the role of spiritual ecology in shifting cultural attitudes and beliefs toward the environment. The research would analyze how, in principle and in practice, yoga may inspire a re-evaluation of the culture of materialism and overconsumption that is prevalent in Western society today. The research would be guided by questions […]

Precarious employment is an increasingly common term used to highlight labour market insecurity (McCann and FUDGE, 2017). In Canada, precarious employment usually relates to atypical forms of work that can present all or some of those characteristics: limited or no social benefits and statutory entitlements, insecurity and low paid, high safety or/and health risks (Vosko, […]

Binary fission, the process in which one bacterium divides into two identical cells, is the most common form of bacterial cell division. However, not all bacteria grow like this. The Streptomyces are a filamentous bacterium that undergo a lifecycle (similar to eukaryotic fungi) which culminates in sporulation. The Streptomyces are a biomedically important bacterium as […]

Power electronics interfaces play a major role in the connection of various components in electrical power systems. This project is focused on interfaces for energy storage systems (supercapacitors), and potentially hydrogen fuel cells. A fast acting and flexible DC-DC converter topology is under-development at Concordia University. One problem is the lack of expertise in advanced […]

Robots and other autonomous machines currently have limited sound awareness and speech recognition capabilities, which limits their ability to interact with humans. Applying insights from cognitive neuroscience provides novel ways to improve these interactions. The primary objective of this proposal is to implement an auditory AI for robotics that finds human talkers in the environment […]

Controlling the location, timing and dosage of drug release is essential in increasing drug efficacy and protecting the body from side effects. Such on-demand, targeted drug delivery is especially important for diseases like cancer, because tumors vary widely patient to patient, and so, treatments should be personalized to suit the patient’s individual tumor characteristics and […]

The project “Challenges and opportunities for conducting physical activity research in the Latin American context” consists of a capacity building experience, in which an international PhD candidate in Epidemiology, member of the Healthy Active Living and Obesity research group, will spend 4 months in a research internship that will allow her to be involved in […]