Identification des partenaires des protéines p190RhoGAP

Les stades les plus avancés du cancer sont caractérisés par la présence de tumeurs secondaires appelées métastases. Elles apparaissent suite à la dissémination de cellules tumorales dans l’organisme. Pour cela, les cellules tumorales acquièrent des capacités de migration et d’invasion. Les protéines de la famille des RhoGTPases sont impliquées dans ces phénomènes, il est donc […]

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A Virtual reality (VR)-based yoga exercise program targeting upper and lower extremities function in stroke survivors who are discharged home

A virtual-reality-based yoga training and assessment platform will be developed as a comprehensive approach for training/improving balance, frailty, and cognitive performance and prevent falls in stroke survivors. The project would have 1) a great therapeutic benefit in terms of increasing rehabilitation outcomes post-discharge and 2) would increase the prevention of further disability. The platform can […]

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Powered Hip Prosthesis

People with an amputation at the hip or pelvis have the most difficulty returning to walking because their artificial limb (prosthesis) must replace the hip, knee, and ankle joints. Current prosthetic hip technologies barely meet the person’s needs, leaving these amputees with few options. This project will build from current powered prosthetic knee technology (Össur […]

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Conception et évaluation d’un système embarqué permettant d’analyserles forces de poussée des athlètes de l’équipe canadienne de patinagede vitesse courte piste

Les connaissances des spécialistes de patinage de vitesse courte piste Canada sur la manière dont patinent leurs athlètes d’élite sont principalement basées sur leur expérience personnelle. Actuellement, le manque de mesures concrètes réduit considérablement les innovations technique et d’entrainement que s’autorisent les spécialistes. L’objectif du projet consiste donc à concevoir un système capable de mesurer […]

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Remote Life Signs and Self-Harming Behaviors Monitoring System

Suicide is one of the most important causes of deaths in the prison environment, both in Canada and internationally. Rates of attempts of suicide and self-harm have been on the rise in recent years. To address this problem, there is a real and immediate need for an automated, private, and effective monitoring system that can […]

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Targeting Semaphorin 3C in Castrate Resistant Prostate Cancer

Prostate cancer is the most common malignancy in men and a major cause of cancer deaths. Androgen deprivation therapy (ADT) is the first-line therapy for metastatic prostate cancer but invariable the cancer regrows despite the androgen deprivation – this regrowth is termed castrate resistant prostate cancer. We have discovered that expression of a specific gene […]

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Amélioration de l’instrumentation tibiale lors de l’arthroplastie du genou

Le système iASSIST® Genou est un système d’assistance par ordinateur conçu pour l’arthroplastie totale du genou. Ce système est composé d’instruments réutilisables, d’un contrôleur ainsi que de senseurs inertiels (des PODs) permettant de déterminer les axes d’alignement du fémur et du tibia par rapport aux repères anatomiques. L’objectif de l’outil est d’aider à positionner avec […]

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An Evaluation of Targeted Physical Environmental Interventions in Louis Brier Home & Hospital

In response to the number of residents at Louis Brier Home living with dementia, this project seeks to implement environmental modifications to support resident orientation (specifically related to the hallways and door frames). Based on the data analysis from the observations and focus groups, recommendations will be made for modest physical environmental modifications to promote […]

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Construction d’une approche d’analyse de la liberté d’exploitation adaptéeaux produits biologiques

La presente recherche traite de l’evaluation des risques faisant obstacle a la liberte d’exploitation (FTO) d’un produit biologique, tel que levaccin XX d’influenza developpe par Medicago®. Elle correspond a la derniere etape du systeme de controle P.I. et a, notamment, pour objet d’identifier de nouveaux risques, mais egalement de mettre a jour taus les risques […]

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Apelin Analog Therapy as an Innovative Treatment for Cardiovascular Diseases

Apelin, an innate peptide, is a critical component of the apelin pathway, which is responsible for regulatory mechanisms of the cardiovascular system. Apelin is downregulated in patients with cardiovascular disease, therefore limiting the cardioprotective potential of the pathway. This project focuses on the optimization of a biological analog, able to withstand enzyme degradation with improved […]

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Automated Change Detection of Serial MR Images Using Compressed Sensing

We aim to develop a new algorithm to detect changes in serial MR examinations. Computer-based change detection system is an important tool to automatically process abundant information produced by imaging systems and assist physicians to identify clinically important changes in the images. Many existing methods are computationally costly. The emerging mathematical theory of compressed sensing […]

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