La rhino-sinusite chronique (RSC) est une inflammation chronique de la muqueuse nasale et sinusale laquelle est l’un des troubles chroniques les plus courants en Amérique du Nord. Deux symptômes communs sont observés chez les patients atteints de RSC, soit une obstruction nasale et une réduction de l’odorat nommée hyposmie. En plus d’une réduction du système […]

The most important structure in the human brain is the cerebral cortex. It makes it possible to perceive our visual environment and sounds, to perform motoric actions such as grasping an object, to speak, to understand speech, etc. The cerebral cortex is a 2-5 mm thick sheet, embedded in the skull. Analysis of MRI data […]

The sport of short track speed skating is an extremely fast paced sport, in which multiple skaters, reaching speeds upwards of 50 km/h, jockey for position on a narrow track. Although skaters wear protective equipment and helmets, concussions continue to plague the health of athletes. Currently, there are no statistics on the ratesand prevalence of […]

Benefit payments totaled 2.5 billion dollars for Ontario workplaces in 2015. The most common injury resulting in a lost time claim was a strain or sprain – indicating despite massive efforts to reduce musculoskeletal injuries by ergonomists, these issues still have a significant financial burden on the economy. An easy-to-use, readily available, and automated physical […]

The information needs of people with colorectal cancer are complex and poorly understood. This project seeks to undertake a narrative synthesis, a form of story telling that brings together evidence in a way that tells a convincing story of why something needs to be done or changed. It helps bridge the gap between research, policy, […]

Non-invasive imaging of hemodynamics is known to enhance screening and monitoring of cardiovascular diseases (a leading cause of death in Canada’s aging population), however clinicians lack an imaging tool that can visualize the complex 3D and dynamic nature of hemodynamics in real-time. To meet such clinical needs, this project will aim to devise the first […]

Better understanding Drug-Drug interactions (DDIs) is crucial for planning therapies and drugs co-administration. While, considerable efforts are spent in labor-intensive in vivo experiments and time-consuming clinical trials, understanding the pharmacological implications and adverse side-effects for some drug combinations is challenging. The majority of interactions remains undetected until therapies are prescribed to patients. We propose to […]

La compagnie Elekta est spécialisée dans le développement d’équipements et de logiciels dédiées aux traitements en radiothérapie pour les centres de traitement de cancer comme celui à Laval (Centre Intégré de Cancérologie de Laval). Les traitements sont administrés par des équipements appelés accélérateurs linéaires qui projettent pendant une durée définie des rayons sur la région […]

DNA and RNA oligonucleotides that fold to form four-stranded structures (G-quadruplexes) are known to bind heme and such complexes to catalyze 1-electron (peroxidase-like) and 2-electron (peroxygenase-like) oxidation reactions. While successful in competing with protein peroxidase enzymes in this respect, G-quadruplex•heme complexes are currently not competitive with protein enzymes with regard to the enantioselectivity of the […]

Personalized health is increasingly gaining public attention in the media as the future of healthcare. Personalized health is the idea that medical treatment will be tailored to the individual based on their predicted response or risks of disease. Omics analysis, defined as the universal detection of different classes of biological molecules, has the potential to […]

Stuttering is a speech disorder that not only affects a person’s ability to communicate fluently and confidently, but can also have a significant impact on their quality of life and mental health. Developmental stuttering typically emerges in early childhood; however, 20% of individuals will continue to be affected by this disorder into adulthood. After decades […]

In the current functional and structural neuroimaging project, we aim to identify functional and structural changes that correlate with disease presence and its severity (staging) and that can serve as a basis for future development of PD neuroimaging biomarkers. To achieve this objective we will use our expertise in functional neuroimaging of the cervical spinal […]