The Dual Effect of Normobaric Hypoxia on Heart Rate Variability and Substrate Partitioning During Exercise and Recovery

)The research proposal is designed to examine the relationship between metabolism and the autonomic nervous system during exercise and recovery. This randomized, controlled crossover design experiment will consist of three sessions. The first session is a familiarization session. The second and third sessions will be the same, except the exercise portion will be done in […]

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Informing the delivery of modern therapies for therapies improving cardiorenal outcomes for patients with type 2 diabetes

Per clinical guidelines, patients with Type 2 diabetes and certain co-morbidities should initiate modern glucose-controlling therapies that also reduce the risk of cardiovascular and renal adverse events, such as GLP-1 RA and SGLT2i medications. But many indicated patients have not initiated these therapies, in part because some primary care doctors are uncomfortable with the complex […]

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L2M Validation / Qc Automne 2025 / Développement d’un Scribe Intelligent pour la Préconsultation Médicale

Le projet vise à développer un système d’intelligence artificielle capable de remplacer le rôle traditionnel du scribe en clinique. Actuellement, dans certaines cliniques à Montréal, les médecins se sont regroupés pour créer des formulaires comprenant des questions essentielles à poser à un patient se présentant avec certains symptômes. Par exemple, dans le cas d’un mal […]

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High-Fidelity 3D Simulation of Soft Tissue Cutting via Adaptive Cohesive Zone Modeling: Toward Digital Surgery

This project aims to improve surgical simulations by developing advanced computer models to simulate how soft tissues behave during surgeries. It will focus on modeling tissue fracture and how surgical tools interact with tissue, considering factors such as tissue anisotropy, residual stresses, and complex tool geometries. Current finite element (FE) models developed at UBC assume […]

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Understanding how Dolutegravir-based antiretroviral therapy modifies the HIV-1 latent reservoir and implications for an HIV cure

Global funding for life-sustaining therapy to treat HIV-1 has become unstable in recent years, particularly in sub-Saharan Africa, where 70% of the 37.9 million people with HIV (PWH) reside. Lifelong adherence to therapy is required as HIV integrates into the DNA of long-lived host immune cells, persisting quietly for decades with the potential to reactivate […]

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comparison of heart rate variability and brain activation during emotional regulation in athletic groups

Stress has been implicated as a significant contributor to both mental and physical illness, and has been shown to compromise psychological well-being. Emotional regulation is the process of monitoring and adjusting emotional responses to environmental stress. Heart rate variability (HRV) and functional magnetic resonance imaging (fMRI) have been used as biomarkers for emotional regulation. Currently, […]

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L2M – BioThera Solutions

We are developing a promising new technology based on extracellular vesicles (EVs, often referred to as exosomes), which are natural delivery vehicles produced by cells. These tiny particles have the potential to transform how we treat diseases by delivering therapeutic ingredients directly to where they’re needed in the body. To bring this technology to market […]

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Impact assessment for Women’s Centres Connect

Women Centre’s Connect (WCC) is launching a province-wide Impact Assessment Initiative that will rigorously measure—and transparently communicate—the economic and social returns generated by its programs, with the explicit goal of unlocking sustained government funding. This project will build a robust evidence framework that traces how WCC’s services move women from economic inactivity or precarious circumstances […]

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L’aide multicritère à la décision pour la priorisation des services au CIUSSS-CN

Ce projet vise à créer un outil d’aide à la décision pour aider le CIUSSS de la Capitale-Nationale à mieux prioriser ses services de santé. Il s’inscrit dans une démarche de recherche-action, en collaboration avec différents acteurs du milieu. L’outil reposera sur une méthode d’évaluation multicritère (AMCD) qui prend en compte des éléments à la […]

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TRLUP-NeuroScope – wearable, AI-integrated, portable EEG device

Current EEG (electroencephalogram) systems used in clinical and diagnostic settings are often bulky, expensive, and require patients to remain in a controlled environment for extended periods. This limits their accessibility and practicality, especially for patients suffering from neurological conditions such as epilepsy who require continuous, long-term brain monitoring to detect abnormal brain activity and predict […]

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Development of an individualized objective-testing app that can establish and analyze cognitive key performance indicators by leveraging artificial intelligence

Cognitive Check is an organization committed to improving diagnosis, management and outcomes of mild traumatic brain injuries (MTBI) such as concussions through an innovative health technology app. The purpose of Cognitive Check aligns with Centennial College and WIMTACHS business strategy and ethos of digital health technology innovation and applied research in healthcare technology. The goal […]

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