Characterization and optimisation of muscle oxygen extraction and performance in elite judo athletes

This project will investigate the determinants of performance in the sport of judo to optimize training and enhance performance development. Judokas must perform multiple high-intensity efforts that cause fatigue, and most of their training is devoted to mitigating the development of fatigue during matches. However, our knowledge of key metabolic responses and adaptations is still […]

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Estuary resilience and recovery following exclusion of a non-native invader, Canada Geese

We need to understand whether estuarine marsh habitat recovers to the same condition quality as undisturbed areas after exclusion of intensive goose grazing. Recovery through natural processes takes longer than restoration assisted by transplanting, however understanding how much faster assisted restoration enables recovery helps inform cost-effective strategies. Non-profit organizations can benefit from academic support to […]

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Using high-throughput mapping techniques to reveal mechanisms of vocal learning

Understanding how humans and non-human animals communicate with each other continues to be a central question in neuroscience. Songbirds serve as powerful animal models for this endeavor because they learn their vocalizations (“songs”) in a manner that resembles how humans learn to speak and because vocal learning in songbirds is regulated by discrete brain circuits […]

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Assessment and selection of competent oocytes for embryo development Year Two

The incidence of female infertility is on the rise in Canada, afflicting up to 17% of woman between the ages of 18 to 34 and with a considerably higher rate of occurrence in woman over 34. Many infertile women are now turning to assisted reproductive technologies (ART) to facilitate conception and child bearing. Female oocyte/egg […]

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Étudier les effets de l’hydroxyde de calcium et de la dermaseptine-1 sur Enterococcus faecalis et Candida albicans

Des millions de Canadiens peuvent souffrir d’infections microbiennes au niveau des dents. Notre recherche vise le développement d’une nouvelle façon de traiter ces infections. Nous étudierons l’efficacité d’un produit nommé la dermaseptine à réduire la croissance des bactéries responsables des infections au niveau de la bouche et des dents. Si ce produit est efficace contre […]

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Understanding molecular, cellular and tissue responses to low-dose / low-dose-rate ionizing radiation

The project will undertake independent and evidence-based research on the effects of exposure to low-dose radiation (LDR). It aims to obtain accurate and unbiased information on the biological responses resulting from exposures to LDR – a cell and tissue stressor. The project will undertake tasks that will identify changes in metabolic processes and physiological systems […]

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Modulation du signal des facteurs de croissance par l’ubiquitylation

Les facteurs de croissance stimulent la prolifération cellulaire. Ils agissent à travers des récepteurs situés à la surface cellulaire et activent des réseaux de signalisation complexes menant à l’expression des gènes. Un contrôle particulièrement efficace de cette signalisation s’exerce par le retrait du récepteur de la membrane plasmique par endocytose. Nous avons récemment montré que […]

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Anti-Inflammatory and Immunomodulatory role of Protein Hydrolysates: Involvement of microRNAs and Gut Microbiome

Studies related to the gut-lung axis have spiraled in the recent year, especially with current challenges related to COVID-19. The role of an optimal microbiome status for a well-functioning immune system is now emerging as a crucial factor to protect against immune-deregulation and infection in sites distant from the intestine. Therefore, this project aims to […]

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Investigating movement-hormone feedbacks as a basis for habitat specialization

In nature, animals must make decisions about where to find food. Looking for food, however, exposes animals to the risk of being eaten by predators and forces them to compete with other animals for food. This combination of risk and competition is stressful, and animals respond by releasing hormones help them cope. Initially, a common […]

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