Transcriptomic responses of in ovo delivered bioactive substances in heat stressed broiler chickens

Heat stress causes significant economic losses to the poultry industry. Several bioactive substances have reported heat stressmitigative properties. However, the conventional routes of bioactive substance delivery, i.e., via the feed or water, limit their efficacy. Delivering these substances via the in ovo route might help overcome the limitations of the conventional delivery routes. This delivery […]

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Combining experiments, genomic tools, and an eco-evolutionary framework to understand the biotic basis of harmful algal blooms

Although evolution is considered a gradual process recent evidence suggests that adaptation can be rapid, particularly when there is genetic variation and selection is strong. Determining whether rapid evolution happens predictably in nature, both at the phenotypic and genomic levels, is crucial to understanding the origins and maintenance of biodiversity. Harmful algal blooms (HABs) pose […]

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Assessing memantine induced mitophagy in a neurodegenerative model of Drosophila

A consequence of aging is the increased risk of neurodegenerative disease. In the pathogenesis of neurodegenerative diseases is the production of misfolded proteins which can clump together and interfere with normal cellular function. Mitochondria are highly important as they produce energy necessary for cell survival as well as regulate the controlled cell death process of […]

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Exploring the boundaries of serial electron diffraction

Serial electron diffraction (serial-ED) crystallography is an emerging structural biology method whereby data are collected from protein nanocrystals using a sub-micron-sized electron beam. The method is set to lead the future of nanocrystallography, given its cost-effectiveness and the small amount of sample required. Combining the expertise of the Colletier and Miller teams, the project will […]

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Using machine learning to explain the fitness landscape of an enzyme involved in antibiotic resistance

An organism’s genome contains the information necessary for its development. Part of this information is used as “instructions” for cells to synthesize molecules called proteins, which perform most of the cell’s functions. However, over time, changes to the genomic information can occur. These changes (mutations) can have all kinds of effects: some might cause diseases, […]

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Network Analysis and Mathematical Modeling of Neuron-Astrocyte Multiplex Net

Understanding and predicting brain activity is the main objective of computational neuroscience. Neuronal cells are the building blocks of the brain and responsible for electrical signaling and cognitive ability. Recent studies indicate that another cell type, called astrocyte, plays an important role as well. These cells have been proposed to interact with neurons and modulate […]

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Develop a test system for the Superficial Digital Flexor Tendon of the Horse

The overall objective of the work is to understand how loading from the different muscle groups affects the strain that develops in the Superficial Digital Flexor Tendon (SDTF) of the Horse. We will be able to learn how the strength and power of each muscle group must be adapted to achieve different strain distributions in […]

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Cloning, expression and characterization of a novel gene involved in Amaryllidaceae alkaloid metabolism

Amaryllidaceae alkaloids (AAs) are a group of specialized metabolites found predominantly in the Amaryllidaceae plant family. Approximately 650 naturally occurring AAs have been identified, many of which possess a variety of potent biological and pharmacological properties. In contrast to the large body of knowledge on the pharmacological and phytochemical aspects of AAs, their molecular and […]

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Toxicité résiduelle et stabilité à la digestion de la zéaralenone-14-phosphate chez le porc

Les mycotoxines contaminent principalement les céréales au champ ou au cours de leur stockage. Elles sont toxiques pour l’homme et les animaux. Avec plus de 56% d’échantillons testés positifs en alimentation animale, la zéaralenone est la mycotoxine la plus présente en Amérique du Nord après le déoxynivalenol. La présence de cette mycotoxine dans l’alimentation, même […]

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Optimization of oat beverage process for sustainability and high nutrient recovery

Plant-based beverages, originally introduced as cow milk alternatives, have attracted great attention from consumers in recent years due to their sustainability and health benefits. Oat beverages has become one of the most successful commercial products in the Canadian market due to the large oat production, high protein and dietary fiber contents and excellent sensory property. […]

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