Healthcare professionals treating trauma patients can vicariously experience trauma from long term exposure to suffering, resulting in compassion fatigue. The impact of compassion fatigue on the psychological well-being of healthcare workers is detrimental, decreasing patient care and retention of healthcare providers. In an effort to reduce compassion fatigue, Mount Sinai Hospital has implemented a 4-hour […]

Protocells are synthetic, cell-like microcompartments designed to mimic key aspects of living cells to provide researchers with deeper insights into primitive cellular functions and behaviours. This research project is aimed to design and synthesize functional polymer coated gold nanoparticles and clusters (AuNP and AuNCs) that are capable of self-assembly into gold inorganic functional colloidosomes. The […]

Candida auris est une nouvelle espèce de Candida découverte depuis 2009, qui s’est propagée dans six continents, causant des épidémies nosocomiales de candidoses invasives. La mortalité élevée et la transmissibilité rendent C. auris un pathogène fongique dangereux pour la santé publique. De plus, C. auris peut développer des résistances à toutes les classes d’antifongiques (azoles, […]

Au Québec, il existe encore peu d’études évaluant les effets aigus et chroniques des herbicides sur les plantes aquatiques enracinées. Une meilleure compréhension des effets des activités agricoles sur les herbiers aquatiques, particulièrement ceux du Lac St-Pierre, est nécessaire à une gestion/conservation adéquate de ces écosystèmes de grande valeur. Ce stage portera en grande partie […]

Having an efficient and scalable manufacturing production process of Adeno-Associated Virus (AAV) vectors remains one of the most challenging problems in the industry for meeting the high demand of AAV for clinical application in gene therapy. The current production process of AAV relies on the co-transfection of three plasmids containing the main virus structural and […]

Heat stress causes significant economic losses to the poultry industry. Several bioactive substances have reported heat stressmitigative properties. However, the conventional routes of bioactive substance delivery, i.e., via the feed or water, limit their efficacy. Delivering these substances via the in ovo route might help overcome the limitations of the conventional delivery routes. This delivery […]

Although evolution is considered a gradual process recent evidence suggests that adaptation can be rapid, particularly when there is genetic variation and selection is strong. Determining whether rapid evolution happens predictably in nature, both at the phenotypic and genomic levels, is crucial to understanding the origins and maintenance of biodiversity. Harmful algal blooms (HABs) pose […]

A consequence of aging is the increased risk of neurodegenerative disease. In the pathogenesis of neurodegenerative diseases is the production of misfolded proteins which can clump together and interfere with normal cellular function. Mitochondria are highly important as they produce energy necessary for cell survival as well as regulate the controlled cell death process of […]

Serial electron diffraction (serial-ED) crystallography is an emerging structural biology method whereby data are collected from protein nanocrystals using a sub-micron-sized electron beam. The method is set to lead the future of nanocrystallography, given its cost-effectiveness and the small amount of sample required. Combining the expertise of the Colletier and Miller teams, the project will […]

An organism’s genome contains the information necessary for its development. Part of this information is used as “instructions” for cells to synthesize molecules called proteins, which perform most of the cell’s functions. However, over time, changes to the genomic information can occur. These changes (mutations) can have all kinds of effects: some might cause diseases, […]

Understanding and predicting brain activity is the main objective of computational neuroscience. Neuronal cells are the building blocks of the brain and responsible for electrical signaling and cognitive ability. Recent studies indicate that another cell type, called astrocyte, plays an important role as well. These cells have been proposed to interact with neurons and modulate […]

The overall objective of the work is to understand how loading from the different muscle groups affects the strain that develops in the Superficial Digital Flexor Tendon (SDTF) of the Horse. We will be able to learn how the strength and power of each muscle group must be adapted to achieve different strain distributions in […]