The goals of this proposal are to develop methods to identify cell subgroups in dopaminergic (DA) neuron cultures obtained by differentiation of human pluripotent stem cells (hPSC), and to exploit this information to improve existing DA neuron differentiation protocols. To realize these goals, we will leverage expertise at STEMCELL Technologies in hPSC differentiation and Simon […]

Aluminum and titanium components fabricated via laser powder bed fusion (LPBF) process have gained industry interest, especially for automotive and aerospace applications, due to their enhanced lightweight and mechanical properties. For a higher part quality and surface resolution, the use of fine powders is desired for the LPBF process. However, the poor flowability of fine […]

Music therapy is an evidence-based effective intervention to promote psychological, social and emotional health, and it is specifically favored by older adults. However, little is known on the efficacy of the AI-assisted empathic music therapy in which the music is continuously adapted to individuals’ mood. To fill this gap, the proposed project will assess the […]

Objectives: The objectives of this study are to use in vitro and in vivo models to validate the hypothesis that the ironchelator, DIBI, can selectively inhibit the proliferation and survival of breast cancer cells and that the combination of this chelator with radiation or standard chemotherapeutic agents (e.g., cisplatin and docetaxel) increases the sensitivity of […]

With COVID and the corresponding shutdowns required of our customer base, our company, and the manufacturing industry as a whole, has become increasingly disconnected. As a result, our stagnant account list has grown substantially. We currently have 1000’s of accounts that were once viable customers that haven’t done business with our company for over a […]

Le Québec vit actuellement un manque criant de main-d’oeuvre. Pour atténuer cette crise, on commence de plus en plus à regarder du côté des bassins d’employés non traditionnels, notamment ceux éloignés du marché du travail. Or, ces personnes ne sont pas toujours équipées en termes de savoirs, savoir-faire et savoir-être pour intégrer durablement le marché […]

The human intestinal tract contains trillions of bacteria that greatly influence the way we absorb and use the nutrients in our food. In the context of obesity, the balance of this environment is impaired which could lead to the worsening of diseases related to obesity, such as type 2 diabetes. This highlights the need for […]

Overexpression of the calcium channel – Transient receptor potential vanilloid type (TRPV6) occurs in many epithelial type cancers [4] and hematological malignancy such as leukemia [7]. However, no correlation of TRPV6 to the deadly bone marrow cancer, multiple myeloma, has been made so far. Recently, we have detected the strong expression of TRPV6 protein in […]

A novel high temperature and high pressure materials test system, a so-called in-situ punch shear test cell, has been developed to qualify materials for reliable service in harsh environments representative of those typically encountered in oil and gas operations. Conventionally, materials are first exposed in harsh environments, then removed from the aging fluids for mechanical […]

Malgré la croissance technologique du domaine médical, les prothèses d’épaule n’ont connu que peu d’amélioration. Toutefois, installer une prothèse est complexe puisque l’ajustement de celle-ci aura un impact direct sur la mobilité et la douleur que le patient ressentira. Afin de maximiser le résultat, Stratera propose de concevoir une prothèse instrumentée permettant ainsi de mesurer […]

This project will explore the potential of agile geographic sensing technologies to support remote terrestrial platforms that are able to access unpaved wilderness environments. Laser scanning and photogrammetric survey systems will be tested to assess their capability to support real-time terrain navigation, spatial situational awareness,

Many problems in fashion originate from over consumerism and resulted in lower quality goods, poor working conditions, and detrimental impact to the planet. The fashion industry has recently shifted toward better environmental practices but focus has been on apparel because shoes are complex products. ARSHAE, located in Montréal, proposes an end-to-end solution that accounts for […]