Formulation and clinical translation of a novel DOX-DelivraTM transdermal treatment for diabetic foot ulcers

This research project aims to develop a novel treatment for diabetic foot ulcers. Individuals with diabetes (3.4 million Canadians) exhibit impaired healing of acute wounds, and 15% (~510,000) are estimated to develop chronic non-healing diabetic foot ulcers (DFUs). DFUs precede 84% of all diabetes related lower leg amputations. Typical DFU treatment is excising devitalised tissue […]

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Super Varnishes for Aerospace Coatings

Organic coatings are used to protect surfaces in many prominent industries such as automotive and aerospace. The industrial partner has found it imperative to develop their varnish for aircraft interiors in-house. They have identified a “super varnish” that must have exceptional resistance to cracking, prevention of shrinkage and adhesion to wood substrates (grouped herein as […]

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Development and commercialization of novel reference material for food allergen and gluten proficiency testing

The planned research program aims to address an existing gap: the lack of commercial availability of reference materials for food allergens to be used in the context of analytical method development, validation and performance testing. In particular, naturally incurred samples representing food matrices where priority allergens are likely to occur, in a controlled and calibrated […]

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Development and commercialization of novel reference material for food allergen and gluten proficiency testing – Year two

The planned research program aims to address an existing gap: the lack of commercial availability of reference materials for food allergens to be used in the context of analytical method development, validation and performance testing. In particular, naturally incurred samples representing food matrices where priority allergens are likely to occur, in a controlled and calibrated […]

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Analysis of the implementation of a Model-Based Systems Engineering approach for the conceptual design of advanced aircraft high-lift system architectures

Today, the development of complex products such as aircraft systems is still mainly based on a paper-based requirements and development process which leads to delays, cost overrun and sometimes failure to respond to customer needs. A structured, model-based design approach is considered promising to bring innovation and optimization in systems architectures. The project aims to […]

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Validation of food allergen analytical methods and their incorporation in food process control practices – aiming for more predictable, risk-based quality management systems for processed foods -Year2

The planned research aims to validate food allergen testing tools from r-Biopharm Canada, and their incorporation in novel quality-management systems used in food production. The first part of the project consists in developing validation criteria for allergen methods under the auspices of the Association of Official Analytical Communities (AOAC) and apply these new requirements for […]

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Développement algorithmiques en imagerie Raman appliqués en génie pharmaceutique

Le contrôle de qualité de produits pharmaceutiques s’effectue par différentes méthodes de laboratoire telles que les tests de dissolution et les analyses de chromatographie en phase liquide à haute performance (HPLC). Ces méthodes sont souvent lentes et dispendieuses. L’industrie se tourne présentement vers l’utilisation de sondes spectrales (e.g. infrarouge, Raman) pour le contrôle qualité. Ces […]

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Développement algorithmiques en imagerie Raman appliqués en génie pharmaceutique – Year two

Le contrôle qualité de produits pharmaceutiques s’effectue par différentes méthodes telles que les tests de dissolution et les analyses de chromatographie en phase liquide à haute performance (HPLC). Comme ces méthodes sont souvent lentes et dispendieuses, l’industrie se tourne plutôt vers l’utilisation de sondes spectrales (infrarouge, Raman). Ces outils, nommés technologies d’analyse de procédés (PAT), […]

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Développements et validations numériques d’outils de diagnostic et d’optimisation pour la conception de ventilateurs

Dans les résidences, le bruit de ventilation est considéré comme une source majeure d’inconfort. La connaissance et l’identification des sources de bruit de ventilateurs sont primordiales pour la conception d’un ventilateur silencieux et énergétiquement plus efficace. Dans le cas des ventilateurs fabriqués par la compagnie Venmar Ventilation ULC. le bruit large bande domine d’une manière […]

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Développements et validations numériques d’outils de diagnostic et d’optimisation pour la conception de ventilateurs – Year two

Dans les résidences, le bruit de ventilation est considéré comme une source majeure d’inconfort. La connaissance et l’identification des sources de bruit de ventilateurs sont primordiales pour la conception d’un ventilateur silencieux et énergétiquement plus efficace. Dans le cas des ventilateurs fabriqués par la compagnie Venmar Ventilation ULC. le bruit large bande domine d’une manière […]

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Engineering fucoidan synthesis

Surgical adhesions can form after many kinds of surgery, and affect millions of patients every year, hindering healing and causing pain and infertility. ARC Medical Devices has shown that treating a surgical site with fucoidan, a polysaccharide extracted from some types of seaweed, greatly reduces surgical adhesions in animals, but a source of pure fucoidan […]

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