Safe Magnetic Resonance Imaging of Interventional Devices

Magnetic resonance imaging (MRI) is a non-ionizing modality; therefore, there is no known damage on human tissue as opposed to ionizing imaging modalities, such as X-ray. Interventional procedures take long time and in order to prevent ionization, interventional MRI is very promising. On the other hand, there are safety concerns because of the possible temperature […]

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Therapeutic Strategies for Restoring Palmitoylation and Autophagy in Neurodegeneration

The cellular clearance pathway autophagy is required for degrading toxic proteins and damaged organelles, but is disrupted in many neurodegenerative diseases. During induction many autophagy regulators quickly localise to membranes from the cytosol. The Martin lab has identified palmitoylation, which involves the addition of the fatty acid palmitate to cysteine residues, as a potential regulator […]

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Effect of Shape Parameterization and Optimization Algorithms on Adjoint Based Aerodynamic Shape Optimization

A very important phase in aircraft design is the aerodynamic design of the wing and various other components: wing-body fairing, tailplane, etc. With today’s computer power and progress in algorithm development, the design is made through complex mathematical models which are amenable to automatic optimization. An industrial adjoint-based three-dimensional viscous optimization framework, developed at Bombardier […]

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Production de bioproduits commerciaux dans un réacteur biologique aérobique d’uneindustrie papetière

L’usine Kruger de Trois-Rivières dispose d’un système de traitement biologique des effluents imposant pouvant traiter plus de 70000 mètres cubes d’eau usée par jour. Suite à la récente fermeture de 5 machines à papiers et de deux coucheuses, le système de traitement biologique des eaux usées par boues activées (aussi nommé un réacteur biologique industriel) […]

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Seismic performance of helical pile groups and their cost efficiency as alternative to driven piles

A new seismic hazard model of Canada will be incorporated in the NBCC2020, which will increase the seismic hazard by 50-100%. Meanwhile, helical piles are a reliable and cost-effective alternative to conventional driven piles because of their fast installation, lower cost and lower labour risk. They are suitable for retrofitting existing deficient foundations because they […]

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Prediction of Vortex Breakdown over Wing Geometries Using Detached-EddySimulation

The formation of vortices and their interaction with the aircraft wing and body is one the most interesting problems in aerodynamics. These vortices are usually generated and convected from different parts of the lift providing devices. Their interaction with the flow field, can case unsteady force and vibration. At some configurations, it can alter the […]

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Determination of oxygen stability and shelf life of cannabidiol oil formulations.

We intend to develop standardized protocols for oxygen stability and shelf life testing of cannabidiol oil formulations. Overall, we will study the effect of time, O2 pressure, temperature, and sample quantity on the oxidation of different formulations, and how this accelerated oxidation profile can be extrapolated/modelled to predict long term shelf life under ambient conditions. […]

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Réduction d’échelle d’un procédé de liquéfaction de la biomasse lignocellulosique résiduelle

La production de biocarburants possédant de faibles intensités de carbone requiert la mise en place de procédés optimisés permettant de valoriser au maximum le carbone biogénique. La mise à l’échelle de démonstration de nouvelles technologies représente donc une aventure risquée, et la conception d’une usine génère souvent des questions devant être répondues rapidement afin de […]

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Photo-curable Polysiloxane Resins for Engineered Ferroelectret Films

Polymer ferroelectrets are light weight and flexible materials that display piezoelectric behaviour. These properties make them ideal for use as transducers in the aerospace industry. However, the traditional methods used to prepare high performance polymer ferroelectrets cannot be used for large scale manufacturing due to poor reproducibility or high cost. Furthermore, these manufacturing techniques rely […]

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SN-38 (or 5-FU) drug encapsulation in Iiposomes transported by magnetotactic bacteria for localizedcolorectal cancer treatment

Cancers are treated today with the appropriate combination of chemotherapy drugs, surgery and radiation. Chemotherapy is almost invariably dosed intravenously, and enters the systemic blood flow where it circulates around the whole body, coming into contact with healthy cells as well as cancerous ones. This systemic dosing has two big problems: too little drug gets […]

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