Scleroderma or Systemic Sclerosis (SSc) is an autoimmune disease characterized by progressive fibrosis of skin and multiple internal organs and prominent and often severe alterations in the microvasculature. Although SSc is the third most common systemic inflammatory autoimmune disease, there is currently no effective disease-modifying therapy for SSc. The overall objective of this project is […]

While studies show that dietary fibres are beneficial in many diseases, they are not digested or absorbed directly by the host, but rather fermented by gut microbes. Fermentation byproducts (mostly short-chain fatty-acids; SCFAs) are responsible for health benefits. Only select inflammatory bowel diseases (IBD) patients benefit from fibres; many patients report sensitivity to high fibre […]

The objective of this project is to research new technologies and methods to help in the assessment and functional imaging of neuroplasticity related to music therapy. The approach utilizes key novel technologies being researched in partnership with Dr. Ryan D’Arcy. It takes advantage of on-going, integrated work with Music Heals to research music therapy as […]

This project seeks to demonstrate the impact of health and life sciences research in the Province of British Columbia. Researchers from Simon Fraser University and University of British Columbia – Okanagan are working closed with the Genome BC and Michael Smith’s Foundation to develop new methodology to assess the value of health and life sciences […]

Substance use significantly impacts the health and health care of many people living with HIV/AIDS (PLHIV), especially those dealing with additional medical, psychosocial, and economic complications. The need for comprehensive care for this population is particularly important given the current opioid overdose crisis in Canada. In response, harm reduction (HR) services (e.g., supervised injection, naloxone […]

Substance use significantly impacts the health and health care of many people living with HIV/AIDS (PLHIV), especially those dealing with additional medical, psychosocial, and economic complications. The need for comprehensive care for this population is particularly important given the current opioid overdose crisis in Canada. In response, harm reduction (HR) services (e.g., supervised injection, naloxone […]

Medulloblastoma is the most common brain tumor in children. It is treated with a combination of surgical resection, chemotherapy and radiation. Radiation to a child’s brain can have harmful side effects that may have implications in later development. We intend to use molecular gene expression to classify archived tumors into 4 subgroups with associated low […]

Brain cancer is the second most prevalent cancer in children. Current treatment options are chemotherapy, radiation, and surgery, which either prolongs the child’s life for only two years or leaves them with negative side effects such as slowed development. Thus, there is a pressing need for new therapeutics. Mitacs Proposal Pambid, Mary One of the […]

The Sorensen laboratory-based Childhood Cancer Research Program is specifically focused on elucidating the genetic and biological determinants of the metastatic process in childhood cancer. Metastatic disease remains the single most dominant driver of adverse outcome in most childhood cancers, particularly in childhood sarcomas. Research in the program is dedicated to uncovering the mysteries of metastatic […]

Dans ce projet de recherche, l’organisme partenaire, le Regroupement des Maisons de Jeunes du Québec vise à dresser, avec le soutien de la chercheure principale et de la stagiaire, un portrait des instances régionales de gouvernance dans les 16 régions desservies et à qualifier l’intervention qui se déroule dans les maisons de jeunes afin de […]

Recent pipeline projects in Canada and the US have attracted lots of attention due to their importance for our future economy and environment. In the proposed project University of Alberta and Shawcor propose to work together towards developing E-smart pipelines and creating defect free system. We will utilize the vast amount of emerging and cutting-edge […]

Despite its growing prevalence of chronic musculoskeletal disease in society, its cause is still poorly understood. Emerging research suggests that degenerative spine disease may be an important facilitator to the development of chronic inflammatory musculoskeletal disease. We aim to investigate the effect of degenerative spine disease on muscle inflammation, pain and dysfunction by using an […]