The supervisors and their colleagues have discovered a number of compounds which have greater toxicity towards different tumours than normal cells. The first step in the proposal is to determine the maximum tolerated dose of the compounds in mice after which the candidate anticancer agents will be administered to a special breed of mice in […]

The increased utilization of HVdc technology around the world has created the need for evaluating the reliability of power systems that contains HVdc facilities. For example, if the generation system is remote and it is connected to the load centre through HVdc links, the transmission may have a significant impact on the overall system reliability […]

The overall goal is to create the backend of a mobile personal organizer that suggests professional events (conferences, colloquia, workshops, exhibitions) and contacts to establish while attending events, to members. Currently, the target audience are professionals in the biomedical domain. Given the need to feed data and meta-data from heterogeneous sources into the application, the […]

Healthy ocean food webs are key to the socio-economic viability of coastal communities in British Columbia. The Vancouver Aquarium’s Coastal Ocean Research Institute (CORI) was established in 2014 to provide an ongoing assessment of the health of Canada’s oceans. This project supports this strategic priority of the CORI initiative and advances the organization’s mission to […]

During primary immune responses, dendritic cells (DC) are the principal antigen-presenting cells (APCs) that initiate adaptive immune responses. DCs present pathogenic antigens (such as virus, bacterium and tumour) to induce CD4 and CD8 T cell responses via MHC-I and MHC-II pathways respectively. Recently, our lab has discovered that CD74 molecules not only promote MHC-II but […]

In typical supermarket refrigeration systems, defrosting can account for up to 30% of the total energy consumption of the system while also having an important impact on the quality of the food. To eliminate unnecessary defrost cycles caused by preset time cycle and implement a “defrost on demand” solution, a robust and low cost frost […]

Le Groupe d’experts intergouvernemental sur l’évolution du climat (GIEC) prévoit, suite aux changements climatiques, une augmentation de la fréquence et de l’intensité des précipitations extrêmes. Les impacts de ces bouleversements touchent plusieurs secteurs, dont la sécurité des infrastructures hydrauliques. Dans le but d’améliorer la connaissance sur ces événements et ultimement d’établir des plans d’adaptation, ce […]

Le Groupe d’experts intergouvernemental sur l’évolution du climat (GIEC) prévoit, suite aux changements climatiques, une augmentation de la fréquence et de l’intensité des précipitations extrêmes. Les impacts de ces bouleversements touchent plusieurs secteurs, dont la sécurité des infrastructures hydrauliques. Dans le but d’améliorer la connaissance sur ces événements et ultimement d’établir des plans d’adaptation, ce […]

The Salish Sea is a temporally and spatially dynamic coastal ocean under strong influence from terrestrial and oceanic inputs, and of major economic importance, due in part to fisheries. The Salish Sea is highly productive, especially from early spring to summer when resident and migratory fish populations are either spawning or entering. The interannual productivity […]

The purpose of this project is to conduct a scientific evaluation of pre-placement functional assessment for Canada Post delivery agents. Within the project, the research team will evaluate how delivery agents (letter carriers) perform mocked-up work tasks (based on actual job tasks observed in the field). Then the research team will evaluate how delivery agents […]

The main objective of the proposed research is to find ways to increase the wear life of gland seals in slurry pumps. Gland seals are subjected to harsh mechanical environments: high pressures, high temperatures, and solid abrasives. If gland seals are not designed properly to withstand these conditions, premature gland failure will occur. There are […]

L’objectif de ce projet de recherche consistera à quantifier l’impact clinique (en termes d’année de vie gagnées, des mesures de sécurité, etc.) des différents traitements en première ligne du cancer du sein métastatique et d’étudier en particulier le bénéfique clinique des médicaments de précision, c’est-à-dire les médicaments accompagnés de diagnostic compagnon, sur le pronostic des […]