In vitro development of LNP-mRNA as a treatment for neurological dysfunction in Gaucher Disease

Brain disorders affect 10% of Canadians, however few treatment options exist for these devastating diseases. We have extensive understanding of what causes many of them, but current medical technology has yet to translate this knowledge into effective treatments. For example, many natural proteins have been identified to hold significant therapeutic promise, but getting these proteins […]

Read More
Identification and validation of novel microvascular smooth muscle cell targets for the treatment of heart failure

In response to heart injury, blood vessels throughout the body constrict. While this response maintains blood pressure, it strains an already injured heart. Reducing blood vessel constriction after heart injury, therefore, is beneficial. Current medications do not target the root cause of the blood vessel constriction. We have identified keys parts of a signalling complex […]

Read More
Predicting emergency department visits and hospitalization among the clients of Nova Scotia Mental Health and Addiction central intake assessment

Mental disorders can have negative impacts on people’s health, quality of life, relationships, and productivity. However, people who are in need of mental health and addiction services encounter significant challenges, including timely access to mental health services. As a result, clients’ mental health needs are not met or not fully met, and their health will […]

Read More
BioWater Pathogen Detection Analyzer Development Project

The BioWater development project will encompass the design, development, fabrication, and validation test of a real-time online pathogen detection analyzer prototype for wastewater. The current development of the prototype BioWater analyzer will focus on (but is not limited to) the detection of the Legionella pneumophila in wastewater from Ontario wastewater treatment facilities (OCWA). CEM Specialties […]

Read More
Climate Crisis and Neonatal Sepsis

Climate change is increasing the spread of bacterial infectious diseases worldwide. Infection causes up to 3 million deaths in newborns in their first month of life every year, a critical period of development.1 External stressors such as malnutrition during pregnancy can impact development of the newborns immune system and their susceptibility to infection for their […]

Read More
Multi-Modal Wild Salmon Enumeration and Monitoring: A Video and Sonar-based Deployment in Indigenous Rivers of British Columbia

We develop a real-time salmon monitoring system and web application that includes automated counting using computer vision technologies, lowering our partner’s technician resources in performing manual counting. We will deploy the monitoring system in at least nine river locations with small computer hardware capable of deep learning acceleration to run the automated counting system in […]

Read More
Application of A.I. Techniques and Remote Sensing to Predict Water Quality

The project will develop an A.I. based model and framework to predict water quality conditions in lakes and/or larger streams using satellite imagery. The approach will be generalized and automated so that it can be easily applied to quantify water quality for water bodies in various regions within Canada. Models will be trained using government […]

Read More
Traffic Estimation and Stable Resource Allocation Using Distributed Machine Learning

The proposed research will develop novel distributed machine learning techniques for stable resource allocation and improving traffic estimation in networks. It is a well-known fact that networks are becoming complex and user demand is growing in many directions including the traditional demand for capacity and less delay, as well as improvements in Quality of Experience […]

Read More