Canagliflozin to improve enzalutamide response and suppress resistance in hormone-sensitive and castrate resistant prostate cancer (PrCa).

In this study, researchers aim to investigate whether canagliflozin, an anti-diabetic agent, can enhance the effectiveness of enzalutamide in preclinical models of prostate cancer (PrCa). Prostate cancer often becomes resistant to current therapies, such as enzalutamide, due to various molecular pathways. Canagliflozin has shown promise in suppressing these pathways in prostate cancer cells and tumors, […]

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Evaluating the Accuracy of Glove-Based Hand Tracking for Virtual Reality Ergonomics Assessments

The specific objective of this project is to compare the accuracy of the Manus Quantum motion capture gloves against traditional hand-held controllers for conducting proactive ergonomics analyses in virtual reality (VR). Digital human model (DHM) hand locations and joint angles will be compared to their ground truth measures derived from laboratory-grade optical motion capture. To […]

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Pistes de conception en design urbain pour créer des milieux de vie inclusifs et adaptés aux personnes âgées dans les milieux ruraux québécois.

Cette recherche examine comment le design urbain peut être appliqué pour créer des milieux de vie adaptés aux aînés dans des zones à faible densité, en particulier les milieux ruraux au Québec. Ces territoires posent des défis spécifiques liés à l’accès limité aux services essentiels, aux difficultés de mobilité, et au manque de cohésion sociale. […]

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Development of rechargeable hybrid aqueous batteries for cost-effective, large scale energy storage

High capacity battery systems are becoming as important as their smaller analogues which are currently in use in mobile devices. Rechargeable lithium-ion battery packs serve as uninterruptible power supplies or energy stores in electronic vehicles (EVs) and realize the EV technology for many countries. This promotes sustainable development while addressing air quality and climate change. […]

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L2M-Image_Synthesize

Medical imaging is a cornerstone of modern healthcare, but challenges like high costs and limited accessibility hinder its potential. This project investigates the use of diffusion models—a cutting-edge AI technique—to generate synthetic medical images for targeted healthcare applications. By focusing on a single imaging task, such as cross-modal imaging or sequence generation, the project will […]

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AI & Chaos Theory-Powered EEG-Based Systems Predicting and Managing Worker Fatigue and Stress in the Mining Industry

This project focuses on developing a smart, wearable system powered by artificial intelligence (AI) and advanced brain signal analysis to help monitor worker fatigue and stress in the mining industry. Mining is a demanding job, and workers often face long hours and stressful conditions, increasing the risk of accidents. The system uses a small, non-invasive […]

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L2M- FlexMatrix: Advanced Cell Culture System with Micropatterned PDMS Substrate and Biaxial Stretching

This project addresses the biotechnology and pharmaceutical industries’ need for mature, physiologically relevant cardiac models for drug discovery, cardiotoxicity testing, and personalized medicine. Existing models, such as human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), lack the structural and functional maturity needed for reliable applications. The UBC MEMS Lab has developed a soft, micropatterned substrate and a […]

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L2M – LinguaSens: Real-time Tongue Pressure Mapping Solution for Digital Therapy

In the field of speech-language pathology, the tongue’s role cannot be overstated. It is crucial for articulating speech sounds and ensuring the safe passage of food and liquids from the mouth to the esophagus. Yet, despite its importance, speech-language pathologists face significant challenges in evaluating tongue performance due to the lack of effective tools. This […]

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L2M – Project Peace

This project aims to create engaging learning activities and a digital interface to help different groups of people understand and talk about important social issues like racism, ageism, cultural differences, and generational divides. The project will focus on four main groups: young children, high school or university students, community members, and workplace teams. By developing […]

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L2M-Long-lasting, ultra safe, and eco-friendly liposome-based sunscreen

Skin cancer, especially melanoma, is one of the most prevalent cancers worldwide, with North America experiencing particularly high rates. Despite the importance of daily sunscreen use, concerns about the safety of traditional UV filters—such as skin penetration and potential hormonal disruption—continue to grow. Additionally, these filters degrade when exposed to sunlight, reducing their effectiveness over […]

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