Development of a SEMA3C targeted therapeutic for treatment of clear cell renal cell carcinoma, lung cancer, breast cancer and colorectal cancer

The major focus of this proposal is to perform preclinical studies to support clinical development of a novel inhibitor for treatment of different caners such as breast, lung, colorectal and kidney. We have recently developed a novel therapeutic protein that selectively inhibits multiple pathways for treatment of advanced prostate cancer. A goal of this project […]

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Anomaly Detection in Event Data

The proposed research project targets anomaly detection of event data. The project has a duration of six months and aims to achieve two objectives: (1) to evaluate the effectiveness of a novel approach for real-world data, and (2) compare it to alternative methods. The intern will use existing research resources, and will apply them to […]

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Développement d’un outil d’Analyse du cycle de vie simplifié pour l’opérationnalisation de l’écoconception dans les PME

Plusieurs entreprises ont un intérêt pour intégrer l’écoconception à leur processus de développement de produits. Cependant, peu d’outils sont disponibles pour obtenir l’impact environnemental d’une décision au cours de ce processus. N’ayant pas un portrait clair des enjeux environnementaux ces aspects sont difficilement des enjeux centraux dans la définition du produit. L’outil développé doit permettre […]

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Data analysis for a Bridge Structural Health Monitoring System (SHM)

The world has many ageing bridge structures which are being used well beyond their design service life time. It is of essential interest for the governments and public to insure safety and sustainability of bridges. One of the most advanced techniques used to investigate the conditions of bridges is the Structural Health Monitoring (SHM). The […]

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Advancing Design for Sea Level Rise—Fraser River Delta

With the onset of climate change, sea level rise is a major global concern including distinct local issues. This project looks at the extremely venerable coastal city/port city of Vancouver. Recent reports call for major infrastructure improvements primarily focused on engineering and not on spatial and design approaches to this challenge. Currently there is no […]

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User Centered Design and Usability of a mHealth intervention for COPD management

Mobile health (mHealth) strategies hold a great promise to enhance treatment outcomes while mitigating health care costs (Hayes et al., 2014). It allows health care providers to tailor treatments to each individual based on their lifestyle. The primary objective is to involve COPD patients and their health care providers in the development of a mobile […]

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Laboratory and Field Assessment of Performance of Treated Wildland Vegetative Fuels

The proposed project will assess and quantify the energy transfer from wildland fires as it relates to coverage of vegetative fuel with wildland fire chemicals for protection of wildland/urban interfaces. The project will extend on preliminary work on the relative performance of wildfire chemicals (e.g., water, gel, foam, and long-term retardants) on forest vegetation. The […]

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Remote sensing of fluvial environments: Automating the freedom space delineation to support sustainable river management at large scale

Recent advances in hydrogeomorphology promote a sustainable, holistic approach to river management based on the concepts of working with nature, where mobility and flood zones are defined to give more space to rivers for fluvial processes and associated ecosystem services to operate. This sustainable and proactive restoration vision, termed “the freedom space for river” concept, […]

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Combinaison synergique de levures, enzymes et acides organiques comme alternative efficace, écologique et économique à l’utilisation d’antibiotiques dans l’élevage de poulets

L’utilisation des antibiotiques pour améliorer la croissance chez les animaux a contribué à l’émergence d’une résistance aux antibiotiques. D’où la nécessité de développer des alternatives à l’usage des antibiotiques. Dans ce contexte, ce projet vise à développer une alternative économique, efficace et écologique, soit une formulation à base de levures à l’utilisation d’antibiotiques chez le […]

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Assessment of Salmonella enterica and Campylobacter jejuni inhibition using lead single domain antibodies in combination with dysregulators of the master protease ClpP

The human pathogenic bacteria Salmonella enterica and Campylobacter jejuni are commonly found in the intestine of poultry. Consumption of infected chicken and eggs, and its derivatives, is the main and most important source of infection outbreaks in humans causing diarrhoea, fevers and abdominal cramps. In some cases, severe diarrhea and dehydration followed by systemic spreading […]

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