Fruit Extract to Dyes – Elucidating the Mechanism of Dye Formation using Genipin to Unlock New Colours

Dyes which are either sourced directly or derived from naturally-occurring products are of growing interest in the cosmetics industry. Sourcing chemical dyes or their close precursors from natural products can significantly reduce the environmental impact of manufacture by reducing the number of derivatization and purification steps. The industrial partner, Inkbox Ink, currently uses genipin, a […]

Read More
Assessment of DNA Ministring technology in cell transfection and the treatment of Colorectal Cancer (CRC)

Despite the power of gene therapy, its successful application to medicine has been diminished due to: (i) high toxicities and potentially fatal adverse effects; (ii) poor transgene expression in target cells; and (iii) extensive vector degradation. While viral vectors greatly improve efficiency, they sometimes lead to cancers due to chromosomal integration and may suffer from […]

Read More
Assessment of DNA Ministring technology in cell transfection and the treatment of Colorectal Cancer (CRC) – Year two

Despite the power of gene therapy, its successful application to medicine has been diminished due to: (i) high toxicities and potentially fatal adverse effects; (ii) poor transgene expression in target cells; and (iii) extensive vector degradation. While viral vectors greatly improve efficiency, they sometimes lead to cancers due to chromosomal integration and may suffer from […]

Read More
Displacement-based Design of Hybrid Steel-timber Structures

Driven by heightened environmental awareness, the construction industry increasingly strives to utilize materials such as timber with a low-carbon footprint in their life cycle. High-strength mass-timber products, innovative ductile connections, and fast computer-numerically-controlled pre-fabrication, combined with changing legislation create better opportunities to also build tall timber structures. However, low ductility and limited tensile strength of […]

Read More
Development of a Borehole Muon Detector for Muon Tomography

CRM Geotomography Technologies (CRM) has developed detectors that are able to measure cosmic ray muon particles underground. By measuring the rate at which these particles pass through the detectors, it is possible to reconstruct a three-dimensional map of the density of the earth’s subsurface above the detectors. This technique is called muon tomography. CRM’s detectors […]

Read More
Development of a Borehole Muon Detector for Muon Tomography – Year two

CRM Geotomography Technologies (CRM) has developed detectors that are able to measure cosmic ray muon particles underground. By measuring the rate at which these particles pass through the detectors, it is possible to reconstruct a three-dimensional map of the density of the earth’s subsurface above the detectors. This technique is called muon tomography. CRM’s detectors […]

Read More
‘Part of the water, part of the land’: Developing Indigenous water legislation for Carcross/Tagish First Nation – Year two

The protection of water is a priority for Carcross/Tagish First Nation (C/TFN) and revitalizing Indigenous legal and governance systems is fundamental to advancing Indigenous approaches to water governance. While the citizens of C/TFN have governed the waters and lands within their traditional territory since time immemorial, their Tagish and Tlingit legal orders have been disrupted […]

Read More
The Cost-Benefit Analysis of Capacity Building Initiative for Rural Community Health Research in Northern Newfoundland and Coastal Labrador (Rural 360 Project)

Faculty Development Programs (FDPs) are widely well-established through the academic medical centers (AMCs); however, little attention has been paid to rural and remote physicians (RRPs), despite their critical role in addressing the priority health concerns of the communities. In response to this, 6for6 and Rural 360 projects have been introduced by the Memorial University of […]

Read More
Inhibiting somatostatin signaling in animal models of diabetes

The prevalence of diabetes is growing rapidly and currently, over 60 million people worldwide use insulin treatment to manage their diabetes. However, insulin treatment can result in hypoglycemia or low blood sugar levels. To date only retroactive treatments are available to treat hypoglycemia, which affects an individual’s quality of life and increases the likelihood of […]

Read More
Inhibiting somatostatin signaling in animal models of diabetes – Year two

The prevalence of diabetes is growing rapidly and currently, over 60 million people worldwide use insulin treatment to manage their diabetes. However, insulin treatment can result in hypoglycemia or low blood sugar levels. To date only retroactive treatments are available to treat hypoglycemia, which affects an individual’s quality of life and increases the likelihood of […]

Read More
Integrating biodiversity functional guild responses to land use and climate change in natural heritage system update

Urbanization continues to drive the land conversion from natural areas to urban uses dominated by impermeable surfaces. This conversion has direct and indirect impacts on ecosystem services that are critical for a sustainable and resilient ecosystem as well as human wellbeing. Habitat removal and fragmentation accelerate biodiversity loss in urban landscapes. Additionally, climate change exacerbates […]

Read More
Integrating biodiversity functional guild responses to land use and climate change in natural heritage system update – Year two

Urbanization continues to drive the land conversion from natural areas to urban uses dominated by impermeable surfaces. This conversion has direct and indirect impacts on ecosystem services that are critical for a sustainable and resilient ecosystem as well as human wellbeing. Habitat removal and fragmentation accelerate biodiversity loss in urban landscapes. Additionally, climate change exacerbates […]

Read More