Development and validation of BRET-based biosensors for drug candidate profiling

G protein coupled receptors (GCPRs) are proteins found at the surface of cells are responsible for activating numerous intracellular signaling pathways and thus are involved in regulating about every physiological response. Activation of GPCRs occurs by compounds as varied as photons, lipids, ions, small hormonal or neurotransmitter compounds or larger peptidic and protein molecules. As […]

Read More
Portrait régional et provincial de l’adaptation aux changements climatiques

Le projet vise à dresser un portrait régional et provincial de l’adaptation aux changements climatiques (ACC) au Québec et d’identifier le niveau de mobilisation et les acteurs actifs ou intéressés à l’ACC. L’étude se situe dans le cadre du programme Par notre propre énergie (2017-2020), mené par le Regroupement national des conseils régionaux de l’environnement […]

Read More
LED Radiation Pattern Modelling

Display technology is ever improving; a current display technology being researched and created includes the use of LED arrays. One array could be used to produce a low quality image with minimal energy, while another more energy intensive array would be used for the sharper aspects of the image. Knowing exactly how these LED’s behave […]

Read More
In Vitro Screening and Validation of Phyto-Cannabinoids in Glaucoma

Glaucoma is the second leading cause of blindness in the world, mainly induced by increased pressure in the eye. Marijuana has been shown to reduce such pressure, thus benefit glaucoma patients. In this project, we test several components from marijuana extracts that are unlikely to cause psychoactive symptoms, for their therapeutic effects on glaucoma. This […]

Read More
Advanced Anode Materials for Next-Generation All-Solid-State Lithium Batteries

Advanced batteries are critical for achieving high-performance electric vehicles (EVs) and supporting goals to reduce greenhouse gas emissions. The prevailing rechargeable Lithium-ion batteries (LIBs) using liquid electrolytes, are the major choice for current EVs. However, these LIBs still suffer from safety, lifespan, and energy density issues. Solid-state lithium batteries (SSLBs) have recently emerged as alternative […]

Read More
Detection of Fights in Crowd Video

Detection of fights and anomalous behavior of individuals in a crowd is a common problem in computer vision. Some tools that currently exist rely on optical flow of tracked features is a sequence of video frames. These motion algorithms are sensitive to independently moving objects in the frame. What constitutes an “anomaly” is context (eg. […]

Read More
Stateful Intrusion Detection using Algebraic State-Transition Diagrams

Increasingly, cyber threats evolve targeting companies, industries and governments. As defense systems are strengthening, threat actors developed new tactics, strategies and techniques to break down security perimeters. Generally, the security of the perimeters are enforced by multiples intrusion prevention and detection tools responsible to provide proactive insights, real-time insights and operational insights for the detection, […]

Read More
Retirement Income and Wealth Management Analytics

The Research Group at CANNEX (formerly known as the QWeMA Group) develops solutions for the financial and insurance industry of North America. Our analytics play an important role in determining the value proposition of investment products. Our solutions help the financial community and public through their financial advisors to be able to make informed decisions. […]

Read More
Processus d’amélioration continue dans les mines

Durant les années où les prix des métaux ont permis une hausse des revenus pour les minières, ces dernières ont constaté que cette hausse ne s’est pas traduite par des profits substantiels pour les investisseurs. Ce constat a amené les minières à réfléchir à leur mode opérationnel et à développer un processus d’amélioration continue inspiré […]

Read More
Collaborative Storytelling – Foundation HCI Research for The Kids Book Company Online

Relatively few interactive narrative-based systems support storytelling as an activity that takes place between children and their parents or guardians. This project is the initial foundation HCI research to explore and prototype tools and methodologies as a contribution to the development of an innovative collaborative online storytelling application – The Kids Book Company. This is […]

Read More
Integrated Project Delivery – Unlocking the Advantages of Innovative Technologies

The American Institute of Architects (AIA) defines IPD as: “…a collaborative alliance of people, systems, business structures and practices into a process that harnesses the talents and insights of all participants to optimize project results, increase value to the owner, reduce waste, and maximize efficiency through all phases of design, fabrication, and construction.” Integrated Project […]

Read More
Elaboration of a Phase II clinical study protocol for the treatment of metastatic non-small cell lung cancer (NSCLC) using AB-16B5, an epithelial to mesenchymal transition (EMT) inhibitor, in combination with docetaxel

The molecular mechanisms responsible for the occurrence of metastatic cancer are beginning to be elucidated with the identification of key regulators. Increasing evidence points to tumor cell epithelial to mesenchymal transition (EMT) as an important contributing process to metastatic evolution. The identification of factors that are stimulated during EMT might provide the means to develop […]

Read More