Development of Cell-Based Functional Assays to Accelerate Commercialization and Therapeutic Application of Recombinant Antibodies

Antibodies are the fastest growing segment of the pharmaceutical market, and with modern engineering technologies antibodies can be programmed to target devastating diseases. Within the immune system, antibodies fight invading bacteria and viruses. High-quality synthetic antibodies directed to disease-related targets have immense therapeutic potential. Development of cell-based assays to enable rapid identification of functionally active […]

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Integrated hydrodynamic and water quality modelling tool for the Toronto Waterfront

The goal of this project is to develop the first ever high definition integrated water circulation and water quality model for the Toronto Waterfront. As one of the most urbanized freshwater ecosystems with complex geometries and physical processes, Toronto Waterfront is in an urgent need for modern scientific tools that can support effective environmental management […]

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Leveraging Historical Development Data to Prioritize Software Testing Efforts

Ericsson Ottawa develops cellular base stations that are components of cellular networks marketed by Ericsson. The base stations serve as the interfaces between mobile devices (cell phones) to wired networks and the internet. These network products require high reliability and availability, which results in the need to perform extensive testing on expensive hardware, replicating complex […]

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Sleep Apnea Screening Algorithms for Pulse Oximetry Utilizing Analog Sensors on a Mobile Device

The research project will develop key algorithms that enable pulse oximetry, on a smartphone, to be used effectively as a sleep apnea screening tool. LGTmedical has developed pulse oximetry that utilizes inexpensive clinical sensors driven by software running on a smartphone, sending the driving signals through the audio port. This technology already operates with clinical […]

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Evolved Radio Access for Wireless Cellular Communication Systems

The continuously increasing demand for wireless access, driven by the increasing requirements of our connected society, is pushing current wireless cellular communication systems to the limits of their capacity. The objective of this project is to continue the successful collaboration with our industry partner (Telus Corporation) to further contribute to the evolution of current generation […]

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Evolved Radio Access for Wireless Cellular Communication Systems – Year Two

The continuously increasing demand for wireless access, driven by the increasing requirements of our connected society, is pushing current wireless cellular communication systems to the limits of their capacity. The objective of this project is to continue the successful collaboration with our industry partner (Telus Corporation) to further contribute to the evolution of current generation […]

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Diversity and structure of coastal eelgrass communities and their importance for maintaining juvenile Pacific salmon

On the coast of British Columbia, both eelgrass meadows and Pacific salmon species are declining, yet eelgrass community dynamics and reliance of juvenile salmon on these communities are poorly understood. We will assemble the first large-scale dataset from monitoring efforts of coastal BC organizations in order to assess eelgrass community diversity and structure across environmental […]

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Diversity of coastal eelgrass communities and their importance for maintaining juvenile Pacific salmon – Year Two

On the coast of British Columbia, both eelgrass meadows and Pacific salmon species are declining, yet eelgrass community dynamics and reliance of juvenile salmon on these communities are poorly understood. We will assemble the first large-scale dataset from monitoring efforts of coastal BC organizations in order to assess eelgrass community diversity and structure across environmental […]

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Integrated Circuits for Modulated Optical Communication Links

High-performance computing and communication infrastructure has reached an industrial scale, with equipment racks 100 meters long interconnected by cables carrying data at speeds exceeding 10Gb/s. This has led to growing interest in optical fiber communication for interconnect within infrastructure computing and communication installations, displacing conventional copper interconnect. Transitioning these relatively short-reach parallel links to optical […]

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The development of single-cell RNA-sequencing methods for identification of biomarkers and therapeutic targets in leukemic stem cells

Targeted cancer therapies have significantly improved the treatment of leukemias, but emergence of treatment resistance and subsequent cancer relapse significantly reduces patient survival. This relapse is primarily caused by the inability of current therapies to eradicate leukemic stem cells. It is currently extremely challenging to study these stem cells, due to its rarity in patient […]

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TARGETING CANCER TUMORS USING A NATURALLY REFINED PARASITE HOST ANCHOR PROTEIN

In this project we will combine knowledge from two different research fields, namely parasitology and cancer biology, to develop a novel approach to target a variety of cancer tumors with high specificity. The malaria parasite P.falciparum has evolved a protein (VAR2CSA) that allows infected human blood cells to bind a sugar structure called CSA on […]

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