L’objectif de ce projet de recherche consistera à quantifier l’impact clinique (en termes d’année de vie gagnées, des mesures de sécurité, etc.) des différents traitements en première ligne du cancer du sein métastatique et d’étudier en particulier le bénéfique clinique des médicaments de précision, c’est-à-dire les médicaments accompagnés de diagnostic compagnon, sur le pronostic des […]

There are multiple academic and non-academic institutions in the province of Quebec that participate in clinical research trials. In the past, each had their own ethics committee. Since all had their own review group and demands, this was creating substantial delays in study start-up and contributed to the decrease number of trials being conducted in […]

The scope of this project is to construct a physics-based analytical model through the bond graph modeling for a reciprocating compressor. The purpose of this model is to quantify input-output relations among mechanical components involved in a compressor, particularly under normal operating conditions. Such a model, once validated and calibrated can serve as a baseline […]

Selective laser meting (SLM) is a promising additive manufacturing process that can be effectively utilized to manufacture structural components with complex geometries. Instead of removing the material, SLM adds the material selectively layer after layer using high power laser beam to form near net shape parts. Due to high cost associated with experimental development of […]

Selective laser meting (SLM) is a promising additive manufacturing process that can be effectively utilized to manufacture structural components with complex geometries. Instead of removing the material, SLM adds the material selectively layer after layer using high power laser beam to form near net shape parts. Due to high cost associated with experimental development of […]

With an average median survival of 14 months, glioblastoma multiforme (GBM), the most common and most aggressive primary brain tumor occurring in adults, represents an unmet medical need and new therapeutic options with a significant impact on patients survival are eagerly awaited. Our laboratory recently identified the enzyme CD73 as a new target for cancer […]

With an average median survival of 14 months, glioblastoma multiforme (GBM), the most common and most aggressive primary brain tumor occurring in adults, represents an unmet medical need and new therapeutic options with a significant impact on patients survival are eagerly awaited. Our laboratory recently identified the enzyme CD73 as a new target for cancer […]

Les procédés biotechnologiques sont des procédés complexes, car ils sont reliés à de nombreux phénomènes biologiques et physico-chimiques. Alors que la compréhension complète de ces phénomènes est encore loin d’être acquise, la supervision, le contrôle et l’optimisation sont la clé de la réussite économique des industries biotechnologiques. Ce projet a pour objectif de concevoir une […]

Rna Diagnostics, Inc. is developing a diagnostic test, named RDA (RNA Disruption Assay) which measures an individual patient’s tumor response to chemotherapy and accurately predicts whether the drug regimen will lead to elimination of the disease. In order to commercialize the intellectual property related to RDA, Rna Diagnostics, Inc. requires mathematical and statistical expertise to […]

Increased interest in active vehicle suspensions has been shown in recent years as active suspensions improve ride comfort and handling over passive suspensions. Active suspensions replace passive fluidic dampers with highly controllable actuators to minimize transmission of road induced disturbances and actively control vehicle’s roll and pitch. However, integration of active suspensions in vehicles is […]

Increased interest in active vehicle suspensions has been shown in recent years as active suspensions improve ride comfort and handling over passive suspensions. Active suspensions replace passive fluidic dampers with highly controllable actuators to minimize transmission of road induced disturbances and actively control vehicle’s roll and pitch. However, integration of active suspensions in vehicles is […]

Le projet proposé étudiera la modélisation de la compacité des particules cimentaires et granulaires pour améliorer la densification des bétons ordinaires ou à hautes performances, réduire leur perméabilité et corrélativement augmenter la durabilité des ouvrages. Le concept de développement durable doit être intégré dans les processus de conception en génie civil en vue de promouvoir […]