Development of a diagnostic assay for first line detection and surveillance of bladder urothelial carcinoma using concurrent biomarker panels from non-invasive liquid biopsies

Bladder Carcinoma (BC) is the fifth most common cancer in Canada. Although most individuals have surgery to remove BC tumors, the risk of another BC developing and/or progressing to invasive disease is high so long-term surveillance is necessary. The current method for screening for BC is not sensitive enough, and individuals often end up undergoing […]

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Production Line Packaging Sensor Validation and Optimization

This research project brings together current academia and a vibrant, growing commercial enterprise to solve real world problems. The industry partner has recently developed a high-tech, sensor-based diagnostic tool which will be evaluated by the graduate student intern. The capabilities and features of the tool will be extended through the innovative, collaborative design efforts of […]

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Measuring Knowledge Translation in Academic / Industry Collaborations

As manufacturing and resource-based industries face growing challenges, Canada’s future increasingly depends on advances in and sustainability of knowledge organizations. Knowledge-based workers comprise a growing proportion of the workforce today. More often than not, they work in the context of large-scale expert networks, spanning across different disciplines and organizations. They rely on software technologies for […]

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Deciphering the role of the tumor suppressor p53 in regulating treatment-induced ovarian cancer cell fate decisions in vivo

As the most lethal gynaecological cancer, ovarian cancers not only threaten lives of many women worldwide, but health side effects also burdens the life of millions patients following treatments. Novel therapeutic methods aiming at increasing the long-term survival of patients and decreasing health side effects associated with treatment is critical. We have already found that […]

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Adapting methods for assessing the impacts of innovation support programs for application to Canada’s clean energy innovation ecosystem

This research project is being undertaken in partnership with The Evidence Network Inc. It will extend the company’s scientifically-based method of assessing the impact of innovation support programs to the clean energy innovation sector. To keep this kind of assessment method scientifically sound requires customization for each particular industry. The established methods have been widely […]

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CYPRESS Video Analytic Framework

High definition acquisition devices have been commonly used in video capture. Millions of videos are recorded and stored daily. Due to the rapidly growing volume, effectively searching and matching the desired video clips from archives has become increasingly challenging. It may need days and weeks to locate the target information, such as suspected criminals, traffic […]

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Développement d’une caméra grand angle miniature

Parmi les systèmes optiques, les lentilles ayant un très grand champ de vue, dites panoramiques, sont des dispositifs extrêmement difficiles à miniaturiser, notamment à cause de leur nombre d’éléments optiques, leur forme et leur complexité. Les techniques actuelles de miniaturisation, utilisées avec succès pour les optiques de téléphones cellulaires, ne permettent pas de miniaturiser suffisamment […]

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Dual inhibition of CA9 and CA12 as effective novel anti-cancer therapy

Hypoxic cells comprise most aggressive and therapy resistant population in the tumors therefore targeting proteins that are essential for hypoxia survival is an effective novel anti-cancer treatment. We have an ability to generate highly specific humanized synthetic antibodies against target of choice. We will generate antibodies against proteins that promote hypoxia survival, test their effect […]

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Dual inhibition of CA9 and CA12 as effective novel anti-cancer therapy – Year 2

Hypoxic cells comprise most aggressive and therapy resistant population in the tumors therefore targeting proteins that are essential for hypoxia survival is an effective novel anti-cancer treatment. We have an ability to generate highly specific humanized synthetic antibodies against target of choice. We will generate antibodies against proteins that promote hypoxia survival, test their effect […]

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