ICES is a non-profit organization tasked with housing and conducting research of Ontario’s health administrative data. Data is available on all legal residents of Ontario, Canada most populous province. In addition, these health administrative data are being supplemented with data from other sources, such as maternal and newborn clinical data, newborn screening data, and immigration data. The rate of immune-mediated disease (such as Type 1 diabetes and inflammatory bowel disease) is increasing rapidly in Ontario children.