Characterization of adverse events, health-care costs and real-world survival outcomes with the introduction of ibrutinib for chronic lymphocytic leukemia/small lymphocytic lymphoma patients in British Columbia

Ibrutinib has proven to be very effective in newly diagnosed and relapsed chronic lymphocytic leukemia (CLL) patients. However, it can cause certain side effects that can lead to early discontinuation of treatment and worse outcomes for patients. The goal of this study is to determine the frequency of side effects in the “real-world” associated with ibrutinib compared to standard therapy using provincial administrative data.

Evaluation of a Regionalized Approach Toward Providing Emergency Medical Services in British Columbia: Is Distance to Services a Critical Factor in Injury Mortality?

One of the primary reasons for this regionalization of health care in British Columbia is so that more resources can be spent on direct patient care and less on bureaucracy and duplication. A critical component of this systems approach is equipping selected facilities with the resources to treat the most severely injured patients. Distance to care is hypothesized to be inversely related to patient outcome – as delays in transporting patients to critical care has a known negative effect on mortality and morbidity.

Towards an Optimal Scale for Injury Surveillance: Evaluating Spatial Dependency and Community Socio-economic Context on Intentional and Unintentional Injuries in British Columbia

Traumatic injuries place a tremendous burden on families, communities, industry, and the health care system. Moreover, the risk of severe injury, especially amongst the young and elderly, disproportionately affects those who are disadvantaged. Investigating the linkage between the environment and injury is complex as the interrelationship between location, socioeconomic status, age, and family demographics is often greater than the sum of their parts. The internship team will propose a geographic information science (GIS) based approach for trauma research.