Investigation of the role of CDK10 in pancreatic cancer growth and metastasis

This collaboration between the Tai Lab at BC Cancer Agency and the biotechnology company STEMCELL will validate a 3D culturing system that supports the growth of normal and malignant pancreatic stem cells. Specifically, we hope to optimize the culturing condition for the growth media to ensure efficient and reproducible outcomes for pancreatic stem cells growing in a 3D system. Various media formulations will be tested to establish a cell culturing system and protocol for the pancreatic tissue.

Molecular-Based Analytics for Prediction and Optimization of Performance

Recent advancements in the study of large biological datasets coupled with powerful machine learning tools and new analytical technologies have opened up the ability to predict risks to health and possibly intervene before disease has manifested. Molecular You has developed a web based interface that integrates all these technologies into easy to understand visual health report for consumers. However, many consumers do not need to worry about health risks, as they are relatively healthy and do not have any health risks identified by our platform.

Development of a new Electronic Fetal Heart Rate Monitoring for use in the Clinical Setting

Fetal Heart Rate Monitoring prior to and during labor and delivery is a common clinical practice, that guides therapy and decision making. A non-stress test (NST), also known as fetal heart rate (fHR) monitoring, is a common prenatal test used to check on a baby's health. The maternal electrocardiogram (mECG) is generally the most prominent signal present in abdominal NST recordings. Therefore, the mECG needs to be removed to enable reliable and accurate fHR detection.

Radon: Building a BC Based Response

Radon is a cancer-causing radioactive gas produced by the natural decay of uranium in rocks and soils. Radon can enter buildings and reach high levels in indoor air (Khan and Gomes, 2017). It is the second-leading cause of lung cancer (after smoking). killing approximating 3200 Canadians a year (Chen et al. 2012). High radon concentrations can be easily remedied, and doing so is a cost effective way to prolong life and reduce death from disease (Gaskin, et. al. 2018). However, Canada’s legal rights and remedies to respond to radon in Canada are largely inadequate (Dunn and Cooper, 2015).

Development of Remedial Action Objectives for McKay River Watershed Impacted by Open Mines and Steam-Assisted Gravity Drainages

Since the 1960s, the lands of several indigenous communities such as the Fort McKay Métis have been largely impacted by open mines and steam assisted gravity drainages (SAGDs). Such oil sands operations have disturbed large areas, changed geology, hydrogeology, hydrology, aquatic and terrestrial environment, and created a linear disturbance. This research project will map and analyze the contaminants of particular concern within the McKay river watershed which will be used to develop remedial action objectives (RAOs).

Simultaneous Analysis of Endocannabinoids with Mass Spectrometry Methods in Human Serum using Point-of-care Collection Devices

Endocannabinoids are compounds produced by the human body that bind to and activate cannabinoid receptors. There are two major endocannabinoids: anandamide (AEA) and 2-arachidonoylglycerol (2-AG). Both play a role in regulating the firing of brain cells in the nervous system and attenuating immune system responses. As such, the endocannabinoid system is implicated in several clinically relevant processes including appetite regulation, pain management, fertility, and beyond.

Phase 1 of Enhanced Measurement-Based Care Effectiveness for Depression (EMBED): A Canada-China Implementation Project (Salary Support for Postdoctoral Research Fellow) - Year two

EMBED (Enhanced Measurement-Based Care Effectiveness for Depression) is a multistage collaboration between mental health researchers and advocates based in Canada, China, USA, and Australia.