Re-conceptualizing youth concussion recovery: A virtual multimedia storytelling project

Youth concussion rates are rising across Canada. In response, efforts are being made to enable the recovery of injured youth. However, little is known about what recovery ‘is’ (how youth understand their own recovery, what constitutes a ‘good’ recovery). This omission represents a major gap in knowledge of youth concussion. This research project will partner with youth who have experienced concussion as ‘storytellers’, to (1) investigate, challenge, and transform conventional ways of thinking about youth concussion, and (2) refine a virtual method for research with this group.

Advancing Post-Secondary Opportunity for Autistic Students

Using simplified language understandable to a layperson, provide a general, one-paragraph description of the proposed research project to be undertaken by the intern(s) as well as the expected benefit to the partner organization. (100-150 words)The project has been developed in concurrence with the Sinneave Foundation’s aim to improve outcomes in education, employment and housing for autistic youth and adults. Post-secondary educational supports and access have been identified as key areas to develop to support the autistic population in their goals.

Feasibility test of a personality-targeted psychosocial intervention for polysubstance use in individuals receiving opioid substitution therapy (OST)pain syndromes, with polysubstance misuse and treatment retention in OST

Secondary analyses of the pathways between impulsivity, emotion regulation deficits, and comorbid. The ongoing opioid use crisis in Canada has been worsened by societal disruptions caused by the COVID-19 pandemic. Effective treatments for opioid use disorders (OUDs) are desperately needed. Opioid substitution treatment (OST), using medications like methadone or buprenorphine, is the most effective treatment for OUD.

Early Biomarkers for Prediction of Chemotherapy-induced RNA Disruption in Tumour Cells

Chemotherapy agents can induce the degradation of a molecule in tumour cells called RNA. We call this phenomenon “RNA disruption”. High tumour RNA disruption after about 1 month of chemotherapy predicts for complete tumour destruction and improved cancer patient survival. We and Rna Diagnostics, Inc. are using this knowledge to predict patient outcome from chemotherapy. Patients with tumours not exhibiting high RNA disruption are likely to benefit from discontinuing chemotherapy and moving on to other treatments.

Oxygen saturation targets in hospitalized children with bronchiolitis: A multi-centre cohort study

Bronchiolitis is one of the most common causes of infant hospitalization and the costs associated with it are large. Since active treatments are mostly ineffective for bronchiolitis, supportive management (including oxygen saturation monitoring) is the main focus of inpatient management. However, ideal oxygen saturation targets for
infants hospitalized with bronchiolitis have not been established. This research study will aim to compare two oxygen target saturations of 90% while awake and asleep vs. 90% while awake and 88% while asleep.

Determining the prevalence and outcomes of transthyretin amyloidosis cardiomyopathy-aortic stenosis patients undergoing valve intervention in New Brunswick

Infiltration of the heart with the protein transthyretin (TTR) commonly leads to the development of cardiomyopathy (ATTR-CM) and heart failure. Once considered rare, advancements in testing have led to the finding that ATTR-CM is much more prevalent. However, no current data exists in a Canadian population. Therefore, this project will determine the how prevalent ATTR-CM is in patients undergoing cardiac surgery at the New Brunswick Heart Center (NBHC). Furthermore, we will determine whether ATTR-CM is associated with worsened outcomes, including mortality, following an intervention.

Evaluating and learning from a mind-body medicine course: An interview-based study

This project learns from the experience of participants in an eight-week Mind-Body Medicine program (MBM). Mind-Body Medicine (MBM) teaches people how to help themselves by uncovering and engaging their inner resources and building resilience, broadly understood. The eight-week MBM program will be delivered through the Iris Centre for Mindfulness, Peace and Healing in Fredericton. The research will involve the analysis of interviews with participants, including those who dropped out.

Digital interventions to improve the mental wellbeing and quality of life of low-income community-dwelling older adults

Our previous research with Mitacs has found that financial burden is one of the biggest negative contributors to the mental health of community-dwelling seniors. We plan to continue to work with the West End Seniors Network (WESN), Vancouver’s second largest not-for-profit seniors’ center, to explore how technology can be utilized to provide mental health aids and services for low-income seniors. The intern will conduct focus groups with older adults to accomplish the research objectives.

Development of Advanced Treatment Methods in Gamma Knife Radiosurgery

This research focuses on two advanced treatment methods for Gamma Knife radiosurgery, primarily used to treat brain tumours, to bring both methods closer to clinical implementation. Dose painting uses medical images for prescriptions to individual voxels (small volume cubes), and tailors treatments to each patient’s tumour biology. Dynamic treatment involves continuously moving the patient while delivering radiation, which may reduce treatment times and improve dose uniformity in treating larger tumours.

First Steps for a Healthy Climate: Exploring grassroots/parent-led community resiliency, civic empowerment and location-based education for climate change

The climate emergency poses a looming existential threat (IPCC 2021), already being realized in BC through forest fires, smoke, drought, and extreme heat events. Babies and young children are high-risk for both present and future climate dangers. Tasked with the responsibility to care and protect societies’ most vulnerable, parents require help, including community resources for increasing family and child capacity to cope with climate change. Such supports are especially important for post-partum mental health.