Whey and milk ultrafiltration (UF) permeate are usually considered as environmental pollutants due to their elevated organic load. Increase of whey production owing to high demand of milk-derived products creates a huge disposal problem for dairy industries. The conversion of lactose, which is main component of whey and milk UF permeate, to value-added ingredients is advantageous. In this project, we will employ a cost-effective enzymatic method to convert lactose into bioactive LBA using whey and milk UF permeate as substrates.
Many methods for providing respiratory support to patients are currently in use, however more commonly available techniques such as Continuous Positive Airway Pressure (CPAP) are not appropriate for ventilation of patients with airborne infectious diseases due to the risk of aerosolization endangering other patients and hospital staff.
Mechanistic models of nutrient digestion, absorption, metabolism, and growth are implemented in industry as ‘decision support systems’ for modern feed formulation and diet optimization, and in academia as research and teaching tools. However, in the equine sector, there has been little focus in modelling which limits the ability of the equine sector to address complex challenges such as interactions between equine nutrition, management, health and welfare. The aim of this proposal is to develop a mechanistic model of post-absorptive nutrient metabolism in mature horses.
The learning of bimanual skills is very important in spine surgery since errors can result in poor patient outcomes. Surgical trainees develop these skills by watching expert surgeons do operations and as they acquire more experience, they are given more responsibility to perform complex operations. The limitations of this learning method are the low numbers of expert surgeons to teach these skills and patients may be at increased risks during this traditional approach to training students.
The aviation industry is a significant contributor to anthropogenic greenhouse gas emissions, and the influence of these emissions is exacerbated by the fact that they are emitted at high altitudes. This project advances the development of fully electric Urban Air Mobility (UAM) systems, which have the potential to significantly reduce emissions relative to existing jet fuel powered aircraft. Unlike conventional aircraft, which use jet fuel-based propulsion systems, UAM is expected to utilize fully Electric Vertical TakeOff and Landing (eVTOL) aircraft.
The marine environment is arguably one of the most challenging for an Unmanned Aerial System (UAS) to operate in. It has to contend with unsteady ship motion, ship airwake, adverse weather conditions, wet landing surfaces and insufficient sensory cues. Sky Canoe is a Canadian company that is producing an advanced autonomous, zero-emissions and long-range cargo rotorcraft to be safely landed and secured on a ship deck. Sky Canoe and the Applied Dynamics Lab (ADL) at Carleton University have partnered to develop and validate a ship landing system for Sky Canoe’s UAS
Presently, tunicates pose a serious challenge for the mussel aquaculture industry in PEI and Atlantic Provinces, which leads to a dramatic increase in the cost of production for both growers and processors. Although tunicate can be applied as the feedstock for the preparation of cellulose nanocrystals (CNCs), an abundant amount of protein-rich liquid stream is often generated. To optimize the tunicate cellulose extraction process and improve the overall economy, this protein-rich liquid stream must be collected and valorized.
Sleep is crucial for the formation of novel memories, and it underpins much of our psychological well-being. Unfortunately, millions of Canadians suffer from sleep difficulties, which are especially prevalent among women and populations with low education and income. These difficulties result in poorer cognitive performance and reduced well-being. Finding solutions to these difficulties is often complicated, as pharmacological interventions often have unwanted side effects, and the most efficient intervention (cognitive behavioral therapy) is hard to access for most of the population.
Multiomics studies of the human microbiome have an enormous potential for understanding the mechanism of biological processes involving the microbial community and the metabolites produced by gut microbiota. We will apply a multiomics strategy to clinical fecal samples using a novel collection device to stabilize fecal metabolites at room temperature, thereby making the standard practise of freezing at - 80°C unnecessary.
Physical inactivity is associated with impaired removal of sugar from the blood after a meal, or insulin-resistance and a reduced muscle mass and fitness. While exercise is well-established to prevent these impairments, it may not be feasible in some clinical conditions. Therefore, passive interventions that mimick the stressors and elicit the benefits of exercise may be required. Electrical muscle stimulation (EMS) and tourniquet induced blood flow restriction (BFR) can prevent muscle loss during inactivity.