The main goal of this project is to design a UAV-based image acquisition system to capture high quality full body images which will be integrated into DermEngine Full Body Imaging (FBI) module. With this system, we intend to achieve consistency between different images that FBI needs to analyze.

For patients with end-stage disease, like cirrhosis, their only treatment option is life-saving organ transplantation. The wait for an organ can take many years over which the patient's condition continues to deteriorate as there is no other treatment. However, maintaining physical activity and a good nutritional intake is necessary to remain on the wait and have successful health outcomes post-transplantation.

We recently developed a rapid and cost-effective pre-clinical technology that is well suited for precision medicine –the ex ovo chicken embryo ChorioAllantoic Membrane (CAM) assay. Our goal is to perform a pilot study that combines tumor genotyping data and the use of personalized CAMavatars, to predict drug sensitivity in renal cancer patients and to test newly developed cancer therapies. We also propose technical advances to the CAM technology and the development of a humanized CAMavatar model that can be used for testing immunotherapy.

The Canadian Institute for Military and Veteran Health Research (CIMVHR), affiliated research partners at universities across Canada, and IBM Canada Ltd. have identified a significant and universal issue facing health researchers that applies to Canadian military, Veteran and family health (MVFH) research and health research for the Canadian population at large.

Funds are requested for one fellow to work in the laboratory of Dr. Simon Graham at Sunnybrook Research Institute, Toronto, in partnership with Siemens Healthcare Limited. The fellow will work on development of prototype instrumentation that will enable a technique called "parallel radiofrequency transmission (PTX)” to be implemented flexibly for research purposes on a Siemens 3 T MRI system at the Institute.

Across Canada, many families struggle to find high quality, affordable child care. Most child care options for families are limited to daytime and weekday work hours; this creates even greater challenges for shiftworkers who rely on paid child care. When child care is not available, mothers usually bear the greatest burden as many women, whether parenting alone or with a partner, act as the default primary caregiver.

Tissue engineering works to replace damaged tissue and organs, and has applications in treating diseases such as diabetes. To improve the performance of tissue engineering treatment and research, our lab has produced the microwell system which creates microtissues in the form of cellular balls. The microwell system has been used used internationally under the brand name AggreWell™, supplied by STEMCELL Technologies and allows researchers to produce enough microtissues to treat diseases in animal models, such as mice.

The recent legalization of marijuana in Canada opens the opportunity to study in detail the effects of cannabinoids on human physiology. This academic-industry initiative will combine resources to isolate compounds from cannabinoids to study their effects on bone cells. Specifically it will examine the effects of cannabinoid compounds on how the destructive osteoclasts form and act upon the bone in vitro. This cell culture work will pave the way for future clinical studies. Bone-wasting disorders like osteoporosis are a major economic burden and inflict a large population of the elderly.

Occupational stress conveys risk of Posttraumatic Stress Disorder (PTSD).