Development and validation of a machine learning predictor for the early detection of prostate cancer

Prostate cancer is the third leading cause of death from cancer in men in Canada. However, prostate cancer is highly treatable if diagnosed early. Unfortunately, due to lack of cost-effective and meaning test detecting the early presence of the cancer. Most prostate cancer (92%) are found when the career is spreading to nearby organs.

Connecting Healthcare Data with the Blockchain

This project focuses on using blockchain technology and smart contracts to manage the health care data access. Blockchain is the distributed ledger based on verified transactions, and the smart contract is the programmable part of the blockchain which can automate more complex transactions. Blockchain provides a secure and durable distributed database to store data accesses and we can automatically grant or revoke access to the users by using smart contracts.

Development of a leadership development impact assessment toolkit

CHLNet identified the need for valid, reliable tools to determine the impact of these health leadership development programs. This project will develop a practical, easy to use toolkit to facilitate the measurement of program outcomes and impacts. The toolkit will be pilot tested and evaluated across the country according to defined selection criteria. The finalized toolkit will be electronic and other knowledge produced during the project will be broadly disseminated.

Assessing the effectiveness of plain packaging in reducing smoking rates: A mixed method approach

Plain packaging refers to standardizing cigarette pack font/color, and removing logos. This form of packaging lowers intention to smoke. However, there is a dearth of research on the direct effects of plain packaging on actual smoking behaviour and the mediation of those effects through increased attention to graphic warnings. The proposed project addresses these two gaps. First, smokers will wear eye-tracking glasses in a lab to determine if plain (vs. branded) packaging increases attention to warnings.

Turning off the “switch”: Preserving the analgesic actions of the endogenous opioid pathway in IBD

Abdominal pain is a debilitating symptom for many patients with inflammatory bowel disease (IBD). An endogenous opioid system emerges in the intestinal tissues during chronic inflammation that acts to dampen such pain and could prevent the need for strong opiate drugs like morphine that can cause serious side effects. However, we have discovered that psychological stress, common in patients with IBD, can block the beneficial analgesic actions of these endogenous opioids and paradoxically can cause them to actually stimulate rather than relieve pain.

Improving Signal Prediction of a Real-time Radiotherapy Beam Monitor using Artificial Neural Network

The science and technology of Radiotherapy for treating cancerous tumor more accurately and precisely is improving constantly with the availability of cutting-edge imaging systems in Radiation Treatment room, and advancements in computer technologies. However, these improvements are associated with complexities and potential risks. To mitigate the risks, a new class of Quality Assurance (QA) systems are emerging.

Development and validation of analysis methods for classification of environments: classification by sound, time, and place

Hearing aids are now fully digital, advanced signal processors that monitor the type of sound coming in to the hearing aid. The sound type is automatically classified into one of several types, such as speech in a quiet place, versus telephone listening, versus in a noisy car. These sound types may require different signal processing from the hearing aid. Accordingly, the hearing aid an automatically switch into different signal processing when the sound type changes. Current methods for sound type classification do not monitor the user’s location.

The impact of single room accommodations on overdose risk for women who use drugs in Vancouver, Canada

People who use drugs (PWUD) face significant barriers in obtaining affordable housing. Single room accommodation (SRAs) housing have thus signified ‘last resort housing’ for structurally vulnerable urban populations, including PWUD. While the health impacts of SRA housing among PWUD are well documented, little is known about the ways social-structural environments of SRA housing distinctly impact women’s risk of overdose.

The role of dairy consumption on variations in response to lifestyle factors in youth and adults

Obesity has increased drastically since the late 1970s and unhealthy eating habits are just one of the causes. Some studies have shown that consuming dairy products such as yogurt helps control body weight in both adults and children. However, factors such as genetics and environment (e.g. dietary and lifestyle factors) may play a role in this response as children who have an obese parent or live in low-income neighborhoods are more likely to become obese adults.

Defining the effects of pineal compounds in longevity and cystogenesis using a Drosophila melanogaster model

Promoting healthy ageing and prolonging life span has become a global priority to improve quality of life and reduce caring costs for age-related diabetes, cancer and heart disease. Pineal gland extract was shown to increase longevity in many organisms and protect against age-related degeneration. We will systematically analyze the life-extension properties of components of the pineal gland using the short-lived fruit fly Drosophila melanogaster.