UPnGO with ParticipACTION: Evaluation of the implementation of a national workplace physical activity initiative

In order to improve the health and work productivity of Canadians, ParticipACTION developed a rewards based, PA tracking intervention called UPnGO with ParticipACTION. The UPnGO program aims to increase the amount of PA and decrease the amount of sedentary activities throughout the workday. Before and after the program, worksites will be assessed to determine what components of workplace environment and policy increase the success of the intervention measured by how employees use the UPnGO platform and changes in average daily steps.

Portable diagnostic device for outpatient BNP detection - Year two

Heart Failure (HF) occurs when the heart becomes damaged or weakened. HF is an epidemic, with approximately 1 million Canadians affected. BNP is an effective diagnostic and prognostic marker for HF. There is a direct correlation between elevated concentrations of BNP in the blood and the severity of HF symptoms. The need for point-of-care monitoring of BNP levels in the outpatient setting is imperative. The main objective is to develop a portable immunoassay-based electrochemical sensor for rapid detection and monitoring of BNP levels in outpatient’s blood, for early detection of HF.

Assessing the validity of virtual simulation as a learning tool in the medical field. - Year 2

With the increasing prevalence of mobile devices, it is unsurprising that they are also being adapted for use as tools for learning and perfecting complex procedures. One of these uses is training health care providers through simulated medical procedures. Two important points should be considered when designing simulated systems to assess the efficacy and efficiency of these teaching tools. 1) Individual differences in emotional biases and learning profiles may necessitate personalized stimulus presentations within simulated environments to achieve optimal and translatable learning.

Pharmacogenetic Biomarker Discovery, Personalized Medicine, and Clinical Test Commercialization in Neuropsychiatry

Pharmacotherapy is one of the primary treatments for psychiatric disorders. Given the variation in individual response, and the current trial-and-error treatment, a more personalized approach is needed. The Mitacs Elevate postdoctoral trainee will gain direct experience with all aspects of using pharmacogenetic testing to personalize medication prescriptions for patients, and the commercialization of the test.

Canadian Communities of Practice in Global Health: meeting the SDG challenge

Canada?s commitment to the Sustainable Development Goals (SDGs) has implications for both domestic and foreign policy in a complex, shifting, and interdependent global health system crowded with multiple actors and stakeholders. The array of activities involved with global public health practice necessitates engagement with health policy and systems research (HPSR), and Knowledge Translation (KT) is critical to bridging the gap between knowledge generated through research and the knowledge that is used to inform policy, practice, and programs.

Investigating the Role of Cannabis Derived Phytocannabinoid Formulations for the Development of Novel Mental Health Pharmacotherapies

Cannabinoid phytochemicals derived from the marijuana plant are increasingly being recognized for their potential in treating a wide variety of mental health conditions. For example, specific compounds found in marijuana such as THC and cannabidiol (CBD) are showing promise as pharmacological treatments for disorders including schizophrenia, anxiety, depression and PTSD. However, very little is understood regarding the underlying neurobiological and molecular mechanisms by which these treatments may produce their clinical effects.

Enhancing Nurses' Role in Opioid Stewardship - Implications for health policy, practice advocacy) and patient safety

Multiple national strategies have been developed address the opioid crisis, however, Canada still remains the second largest consumer of prescription opioids. These drugs can have negative effects on consumers because they have addictive properties so therefore consumers may become addicted to these drugs if there are not taken as prescribed. For other drug classes such as antimicrobials, there have been programs developed to improve prescribing and hence patient outcomes.

Patient localization and identification using a Bluetooth-based sensor network

In general, hospital based medical personnel usually have little or no objective data describing an individual patient?s pre, intra and post-operative (perioperative) movement and activity. We are developing low cost and easily deployable technologies to monitor patient activity patterns and the associated intensities. We want to objectively identify medically important indicators of normal versus abnormal postoperative evolution.

SWAVE Ultrasound Elastography

Organ health is often tested today by biopsy, which involves placing a needle into the body and taking a small tissue sample for analysis in a lab. Researchers at the University of British Columbia invented a new technique to measure the health of tissue without a needle. This technique is called Shear Wave Absolute Vibro-Elastography (SWAVE) and it measures tissue elasticity by recording the small shear waves that result when tissue is vibrated with a loudspeaker-like device pressed against the skin.

Characterization of cell signaling in response to ultraviolet radiation after treatment with an oral skin-care supplement

Bend Beauty is a Halifax based company involved in the research, development, and marketing of oral natural health products for use in skin-care and anti-aging. Bend?s core product, Anti-Aging Formula, is a mixture of the active ingredients fish oil, borage oil, lutein, zeaxanthin, and vitamin D3. An eight-week human clinical study demonstrated this product increases skin?s resistance to sunburn. However, the mechanisms that are responsible for this photo-protective effect at the cellular level remain unknown.