A novel scaffold for tympanic membrane repair

The ability to hear, and the quality of our hearing, depends on the health of the eardrum. Eardrum perforations due to diseases and accidents can be treated using grafts, such as autologous grafts, allografts and xenografts. These replacements suffer from various limitations such as donor site morbidity, long operation time and healing time, and risk of infection transmission, and more importantly, none of these grafts are able to replicate the complex microanatomy for sound quality reproduced by the native eardrum.

Development of an Actigraph System for Sleep-Wake Identification

The main objective of this project is to design a proper algoritlun for analyzing COPD patient's sleep data as an important feature in patients treatment procedure. The data would be gathered by a novel wrist wearable actigraph with high accuracy technology. The wearable wristactigraph will allow more reliable data collection because the subjects can use it in their own home environment and there is no limitation for the length of data collection period. The intern will receive the proper raw data gathered by the actigraph, and focus on the analysis part of the project.

Raman Spectroscopy for in vivo Classification of Peripheral Lung Nodules

In Canada the five year survival rate for lung cancer is only at 15%. There is a great need to be able to detect the disease at an earlier stage which would lead to a better prognosis and outcome for the patient. Although many technologies and medical devices have been in use for standard procedure in the last decade, there are few which can detect lung lesions in the deeper portion, the periphery of the lung with reliability. The best option presently is called radial ultrasound, a device which focuses on tissue density but does not illuminate biochemical characteristics.

Optimization of a Dermoskeleton for Human Performance in Clinical and Occupational Applications

Physical disability in Canadian adults is largely due to painful mobility impairments, with the most common cause being diseases of, and injuries to, the musculoskeletal system and connective tissues (MSK disorders). MSK disorders are generally associated with natural aging, but are also caused by occupational injuries as well as brain or spinal cord injury or disease. The cost of these conditions to the Canadian Health Care system is in the tens of billions per year.

A mixed-methods project investigating HerSwab™ and arts-based education as integral components of culturally acceptable cervical screening in Northwest Ontario First Nations communities

Specific strains of the human papillomavirus (HPV) can develop into cervical cancer. Screening for these types of HPV has been shown as a better early test for cervical cancer. Samples for HPV testing can also be collected by women without going into a clinic. This selftesting method may be a good cervical screening option for women who might not participate otherwise. Certain cultural groups, such as First Nations women, are less likely to participate in cervical screening than the general population. As a result, First Nations women have more diagnoses and deaths from cervical cancer.

Online seizure detection using EEG-based features of neural rhythms measured from a wireless headset

Avertus Epilepsy Technologies Inc. is building a wireless headset that records brain waves (EEG) without requiring extensive, time-consuming, and uncomfortable patient preparation. Avertus’ SMART (Seizure Monitoring at the Right Time) Headset is a patient focused, point-of-care monitoring and detection system. Worn during the day or just at night during sleep, the SMART Headset represents safety, response when needed, and peace-of-mind. For drug companies and treating physicians, the SMART Headset provides an objective measure of seizure occurrence to assess drug efficacy.

Low-power EEG headset for remote monitoring and warning system

Avertus Epilepsy Technologies Inc. is building a wireless headset that records brain waves (EEG) without requiring extensive, time-consuming and uncomfortable patient preparation. Avertus’ headset is a patient-focused, point-of care monitoring and detection system. To design the wireless EEG headset, commercially available dry electrodes will be analyzed and characterized to determine the optimum properties for better EEG recordings. A miniaturized circuit board will be designed for each electrode to make active electrodes that can provide a high quality EEG signal right on the headset.

A wireless headset for power-aware EEG/non-EEG signals processing and seizure warning

Epilepsy is a debilitating neurological disorder affecting approximately 50 million people worldwide (World Health Organization). This project proposes to develop a SMART (Seizure Monitoring At the Right Time) Headset for these patients to monitor their brain signal and track their movements, heart rates and breathing patterns. This headset will have new types of sensors suitable for long term usage and sleep.

Facilitation of early mobilization after colorectal surgery: a randomized controlled trial

There is growing evidence that outcomes after colorectal surgery are improved with the use of perioperative interventions combined into an enhanced recovery program (ERP). Encouraging patients to achieve specific daily nutrition and mobilization goals postoperatively is an important aspect of ERPs; however, it is not known whether the achievement of these goals needs to be facilitated by a member of the healthcare team. This study aims to evaluate the extent to which postoperative recovery is influenced by facilitation of nutrition and mobility.

Systems and methods for planning and guidance ofneurosurgical procedures

Synaptive Medical Inc together with researchers at Western University, are developing a new Magnetic Resonance Imaging (MRI) platform customizersd for clinical neuroimaging. This proposal is to fund a range of student and post-doctoral training activities associated with the development and testing of this new system. The program will also support the development and testing of MRI-compatible devices and technology for use with the new platform.