Vitamin deficiencies are one of the key reasons for infant deaths and a variety of diseases for adults including breast cancer, prostate and cervical cancer, rickets, schizophrenic depression, etc. An invention of a low-cost Lab-on-a-Chip (LOC) microfluidic platform for the detection of Vitamin D and Vitamin A would be an answer for the potential multi-billion dollar market around the globe and represents one of the most desperately needed devices to enhance public health and prevent vitamin deficient related diseases.