Qualitative Data Collection for Development of an Electronic Application to Promote Home-Based Self-Care in Older Heart Failure Patients: Patient and Informal Caregiver Perspectives

Heart failure (HF) is one of the leading causes of hospitalization and rehospitalization in older adults, yet the majority of HF-related readmissions are preventable if patients can manage their treatment at home. One method to help patients who require extra assistance in following their treatment is through mHealth applications. However, these applications are not usable for many older patients due to their complicated design.

Evaluating a Single-Site Supportive Housing Program for People with Serious Mental Illness and Histories of Homelessness

This project will involve an evaluation of a program to house people who have serious mental illness, and who have had experiences of homelessness. There will be two parts to this study. First, the study will examine how this program has been implemented. A study of the implementation of the program will provide information that the program can use to improve how the program functions. Second, the study will examine the outcomes for people who are housed through the program. A key outcome to be examined will be whether people who are housed able to keep their housing.

Optimizing Movement in Children Study (OMiCS)

OMiCS represents a broad research initiative exploring the relationship between physical literacy (PL) in children and markers of biological health. The research seeks to expand on the literature surrounding the components of PL: physical competence, confidence, and motivation for being active, and determine whether any of these components can shift objective biomarkers of health (the “omics”).

Exploring the lived experience of survivors: The link between intimate partner violence (IPV) and traumatic brain injury (TBI)

Past research has established that a high percentage of women in violent relationships experience a traumatic brain injury (TBI), with one article estimating approximately 23 million women in the US living with a TBI from intimate partner violence (IPV) (Ivany & Schminkey, 2016). While previous research has focused on establishing the link between IPV and TBI, further research needs to be conducted into the experiences of these women. The present project seeks to do exactly that, through interviewing of 6-8 women from The Cridge Centre for the Family.

Evidence-informed Planning and Evaluation of Community Transitions: Impact on Health and Quality of Life

St.Amant is an organization that offers services to support individuals with developmental disabilities. Many of St.Amant’s services are shifting to provide the most inclusive, supportive, community-based services with the intention of enhancing health, access to healthcare, and quality of life of persons served and that of their families and caregivers. One of the current service changes is transitioning 75 individuals from River Road Place (RRP) to a variety of community-based residences.

Evaluation of targeted alpha-therapy on patient-derived Glioblastoma cells

Glioblastoma multiforme (GBM) is the deadliest form of human brain tumors, systematically recurring despite multimodal treatment. As a consequence, the average patient survival is less than 15 months, and is thought to be linked with the presence of brain tumor stem cells (BTSCs) that are implicated in treatment resistance. GBM BTSCs are radiotherapy and chemotherapy resistant, and BTSCs escaping treatment may explain tumor relapse. In the current era of precision medicine, targeted radiotherapy constitutes an attractive strategy for treating intractable disease.

CyTOF-based characterization and isolation of MDSC subsets

Myeloid-derived suppressor cells (MDSC) are an unusual type of blood cell that is able to potently turn off immune responses. These cells are not normally present in healthy individuals, when a tumour is present, MDSC can block clearance of the tumour by the body’s immune defenses. A better understanding of how MDSC shut down tumour clearance would greatly improve the success of cancer treatments. Unfortunately, MDSC are difficult for scientists to study because there is currently no effective method to isolate them in pure form.

Physical Activity Opportunities in Saint John, New Brunswick: A Neighbourhood Assessment by Income

Physical activity can help people prevent and manage diseases such as heart disease and diabetes. Currently, many Canadians are not sufficiently active, citing lack of time, money, knowledge, and access to physical activity programs as barriers. This compilation of physical activity programs in Saint John, New Brunswick, will gather details of the types of physical activity programs available and will map them by average income in local neighbourhoods to determine if access is equal for all.

Examining Canadian Student Smoking Behaviours

The project is to examine the determinants of e-cigarette, tobacco and marijuana use among Canadian students. Specifically, we intend to determine what are the major risk factors associated with e-cigarette, tobacco and marijuana use, and to identify strategies that can be used to help address these issues. Statistical analysis will be conducted to measure the relationship between the risk factors and outcome (e-cigarette, tobacco and marijuana use).

Regulating Abnormal Connectivity in Posttraumatic Stress Disorder via Real-time fMRI Neurofeedback

Patients with posttraumatic stress disorder (PTSD) are characterized by decreased prefrontal cortex (PFC) regulation on hyperactive emotion generation regions, such as the amygdala. Real-time (rt)-fMRI neurofeedback allows for localized brain regions to be self-regulated through neuroimaging signal feedback. Recently within our lab, learning to decrease amygdala activation via neurofeedback was shown to normalize the neural circuitry maintaining PTSD, which was negatively correlated to symptoms.

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