Development and Validation of a Protein-Protein Interactions Modeling Platform for Rapid Affinity Predictions and Pharmaceutical Applications

Developing a drug for new diseases cannot only be challenging but also time consuming. From the identification of a druggable target to a compound which can improve a condition it usually takes more than 12 years. Since there is basically an infinite number of possible compounds which can be turned into a drug it is literally the problem of finding a needle in a haystack. The trial and error method of making molecules in the laboratory and testing their efficiency has been proven successful for over a century.

Machine Learning for Modeling Soil-Tool Interactions

When construction equipment digs, this generates a complex set of physical interactions between the machine and the soil. Being able to accurately simulate such interactions in real-time opens the door to improved operator training and even adaptively-tuned digging operation that optimize the energy-efficiency of construction equipment. With recent advanced in artificial intelligence (AI), this is now within reach.

Automatic matching of service offers to calls for tenders

The process for responding to tenders is very long, arduous and involves many repetitive tasks. Among these, it is necessary to read the invitation to tender in order to find the different requirements, important dates, legal obligations, constraints of presentation of the response, etc. All of these factors are used for the prequalification of a tender and for the drafting of the tender. These requirements are generally expressed in the form of free text.

Novelty Detection in Lunar Analogue Terrains

Lunar and planetary rovers are faced with a high volume of data from their sensors and cameras, and yet decisions must be made rapidly to prioritize to which crater it should drive up to and of which rock it should take a closer look. In Canada’s intended upcoming exploration of the Lunar surface aboard short-timescale commercial missions, these considerations are of utmost importance.

Real-time surrogate safety analysis solution using Lidar technology powered by artificial intelligence

The safety of intersections, interchanges, and other traffic facilities is most often assessed by tracking and analyzing police-reported motor vehicle crashes over time. Given the infrequent and random nature of crashes, this process is slow to reveal the need for remediation of either the roadway design or the flow-control strategy. This process is also not applicable to assess the safety of roadway designs that have yet to be built or flow-control strategies that have yet to be applied in the field.

Development of advanced planning and estimating model for scaffolding manhour

Heavy industrial construction projects consist of oil refinaries which generally involve complex structures, large-scale sites, and large numbers of workers from different disciplines such as civil, mechanical, and chemical. These disciplines may require similar or completely different scaffolding systems in order for workers to not only access their working areas but also move material horizontally and vertically.

Development of a solution to assess the quality and to optimize AI-based video codecs

Current video codecs consider algorithms to analyze video imagery in order to find out which bits can be removed for file size reduction without subjective video frame degradation. Integrating AI with encoding process improves the quality of encoding and decoding. AI permits the software to proactively assess the quality of the encoded video before transmission. This allows the compressing system to detect and remedy any possible artifacts in the video frames.

Using semi-supervised learning for classification of sport images

Artificial intelligence (AI) is rapidly becoming one of the most critical aspects in both business and science, and an increasing number of leading technology companies in Canada are at the forefront of AI development and innovation. The proposed research project aims at developing AI algorithms that have the ability to accurately classify the sport practiced or the sporting equipment present in an image.

An efficient heuristic algorithm for laboratory analysis profile selection

In health care industry, the tests of laboratory analysis are organized and priced in the format of profiles. Each profile contains a specific group of tests. The price of a profile is usually lower than the sum of the prices of individual tests included in the profile. In this project, the intern will develop a special optimization algorithm for selecting test profiles and/or combinations of test profiles to cover the list of tests required by a patient. This is an important component to enable an online price estimation service provided by Medialpha.

Future Safe: Designing Efficient Face Masks in the Era of COVID 19

With the surreal times we are living in the context of Covid-19, wearing face masks has become a global public necessity. While many people are wearing face masks, not all masks are created equal. From very expensive high-tech respirators with multiple layers of filtration, to homemade face masks using less than ideal fabrics, the general public has become aware that covering their faces is a big factor that can reduce contagion. For the general public, effective face masks are difficult to breathe in, and those that let too much air flow are not effective.