Advancing Bio-materials Production Services - Year two

Bio-materials can reduce our dependence on fossil fuels, greenhouse gas emissions and facilitate a rapid transition to a bio-basedleconomy. Thus, developing novel and innovative technologies and products related to bio-materials sectors is crucial. This has!resulted in extensive research into the development of biomaterials. Most research efforts have focused on materials selection,\'fabrication, and optimization of bio-materials\' performance through experimentation, trial-and-error, and microstructural analysis.

Exploring patient and provider perceptions to guide optimization of electronic order sets and digital educational platforms for cirrhosis care

People with cirrhosis, a progressive scarring of the liver, often experience frequent and prolonged hospitalizations which have significant impacts to their quality of life. There are many areas for improvement in cirrhosis care such as the enhanced promotion of complication-specific order panels like that for hepatic encephalopathy, a serious complication caused by a buildup of toxins in the blood and the most common cause of hospitalizations.

Automated Scanning Probe Fabrication for Atomic Scale Devices - Year two

With our increasing dependence on technology, the total energy consumption from electronic devices for computation is projected to surpass all other contributions. By creating atomic-scale devices at the fundamental limits in size and energy cost, we can reduce their overall energy consumption while increasing computational power. While proof of concept devices are already routinely created, a fully automated fabrication procedure is necessary to successfully merge this technology with current electronic manufacturing processes.

Engineered Nanoparticles for siRNA Therapy of Blood Cancer

Nucleic acids such as DNA and RNA offer exceptional opportunities to fight against infectious and genetic diseases. To use nucleic acids effectively in a clinical setting, one needs to use effective delivery vehicles that can deliver the nucleic acids into the diseased cells. This project will develop effective delivery systems for this purpose. The delivery systems will be used to deliver RNA and DNA based therapeutic agents in 2 diseases, namely Coronavirus disease 2019 (COVID-19) and hematological cancers.

Modeling of closed-loop geothermal systems

The research program will provide a fundamental understanding of the thermo-hydro-mechanical performance of closed-loop geothermal systems to extract geothermal energy. The findings from this research program will play a vital role in assisting the design of closed-loop geothermal systems and assessing project feasibility. The proposed research will help Canadian geothermal companies take the lead in understanding the design and performance of closed-loop geothermal systems.

Design and Development of the Smart Friction Pendulum System (FPS) for High-Rise Buildings to cope with seismic loads

Buildings are vulnerable to moderate and powerful earthquakes. In order to keep their functionality during and after the seismic events, structural control systems are the promising candidates to be embedded in the buildings in which they dissipate the energy towards the building and separates the movements between the soil and the infrastructure. One of the common systems for this protection is the friction pendulum system (FPS), but it has the disadvantage of losing position once an earthquake happens.

Indigenous Hub for Sport and Wellbeing

The project presents an opportunity to support the health and wellbeing of maskêkosihk’s (Enoch Cree Nation’s) Indigenous youth through building capacity for sport and recreation. Working alongside Ever Active Schools the initiative will create a Hub for Sport and Wellbeing to benefit Indigenous youth and their community.Building sport and wellness capacity focuses on barrier free participation, official and coach training and event management all through peer mentoring and positive community experiences.

Using administrative data to predict health outcomes: a machine learning approach

Adverse events due to benzodiazepine use and falls are important clinical outcomes in older adults. As well, high-cost users of the health care system, although small in number, are a substantial burden with regards to health costs. Continued use of BZRAs in older adults is concerning from a public health standpoint; 1 in 3 older adults experience a fall in the community; 5% of health care users consume about 60% of hospital and home care spending. Being able to identify these individuals would add to the current efforts to reduce health care burden.

Exploring the value and viability of integrating webcam-based eye-tracking into user experience research

While it feels simple and easy to navigate a daily activity like drinking your morning coffee, in the background, our brain and eyes are tirelessly working to make sure we don’t spill our boiling hot brew each time we reach for a sip. By studying these kinds of simple movements, we’re given a window into the complicated eye-hand coordination system that guides us perfectly through our world. What’s more, these insightful movements aren’t limited to just the “real world” – there’s a lot of value in exploring eye-hand coordination in the online / computer-based world we reside in more and more.

Sustainable Materials and Manufacturing for Resource Sector Applications

Maintenance, repair, and longevity of operations in the natural resources sector continues to be a major operational priority for the sector. The sector spends more than $3B per annum on maintenance and repair issues, and when parts or equipment fails, the sector loses at least an additional $5 to $7B in revenue.