Investigation of Raman Spectroscopy for Commercial Clinical Chemistry Applications

The project aims to address the issue of the lack of access to basic blood tests in a majority of the world’s population. We will explore the potential of Raman spectroscopy to provide a reagent-less alternative to traditional clinical chemistry methods. By proving that Raman spectroscopy, in conjunction with advanced machine learning, is able to quantitate critical yet low-concentration analytes, it is possible to develop a purpose-built, commercial, reagent-less clinical chemistry analyzer platform providing critical insight into the health of patients in low resource settings.

Lock-in detection of Raman resonance (LIDORR) in the presence of overwhelming fluorescence

Efforts to sequester atmospheric carbon in soil require effective monitoring methods. Soil water content confounds the conventional application of infrared absorption. Raman spectroscopy contends well with water, but suffers from the overwhelming fluorescence typically encountered in the analysis of soil samples. Here we propose to combine an modulated two-colour illumination scheme with antiphase lock-in detection that will serve to suppress fluorescent backgrounds and uncover Raman signatures of organic substances captured in soils.

Formulation of sustainable amino polyolefin coatings with improved adhesion and corrosion protection

Corrosion is the destructive attack of a metal by a chemical or electrochemical reaction with its environment. Corrosion of industrial and mechanical infrastructure causes severe economic losses. Canadian corrosion-related expenses amount to $41 Billion CAD annually. The extensive oil and gas pipeline networks in Canada require approx. $1 Billion CAD annually for replacement and/or maintenance. Catastrophic, corrosion-related accidents in the pipeline sector pose a severe threat to the environment, property, and human life.

Exploring climate action pathways towards a broader, deeper social mandate for a net-zero carbon economy

Climate change is understood variously across populations, and climate action strategies receive varying degrees of support. This study will explore climate action pathways towards a broader, deeper social mandate for a net-zero carbon economy. It will specifically identify the communication and engagement strategies that are most resonant with certain segments of the population in BC, as well as more broadly in Canada.

Synthesis, evaluation, and scale-up of sulfur-containing lipids

In 2021, over 2.2 billion doses of lipid nanoparticles containing mRNA are to be produced. The world’s largest vaccination campaign for a truly devastating pandemic was initiated as a result of technology developed by the principles in this application. RNA-based vaccines have been the fastest vaccines to be ever developed, with some of the highest efficiencies reported. In order for mRNA to exert its function, it needs a delivery system to take it from outside to the inside of a cell.

Understanding how waistband height and tightness changes respiratory function

Our abdomen can contract in order to help us breath. Restricting our abdomen has previously shown to reduce the function of our lungs at rest, and change the way we breath during exercise. Women's athletic apparel has trended towards high-waisted, lower body garments. A high-waisted band, although not as severe as abdominal strapping, can apply pressure to our abdomen, which can potentially increase our abdominal tone. The purpose of this project is to measure how the height and fit of a waist-band can affect breathing during rest and static exercise.

A Machine Vision- and AI-Based Solution for Optimal Comminution in Mineral Processing Circuits

Comminution, the process of reducing particle size so that valuable minerals can be liberated from the ore, consumes most of the energy used in mining operations. This process consumes an estimated four percent of the world’s electrical power and accounts for 50% of a mine site’s overall power consumption. Although mine-to-mill optimization strategies have been discussed for the past three decades, they have had little overall impact on the industry.

Simulation and Design of Next Generation Single Photon Sensors

Photons are particles of light. While countless numbers are emitted from a light source to illuminate a room, sensitive electronics can detect light down to the level of a single photon. These electronic devices, known as single photon avalanche diodes (SPADs), use a process that triggers an avalanche of electrical charges, which can be measured as an electrical current. SPADs have applications in next generation camera systems, autonomous vehicles, and even quantum information processing.

Development of Metallurgical Testing Methodologies to Assess Sensor Based Sorting

Sensor Based Sorting is a relatively new technology for the mining industry. The ability to use sensor to classify particles or bulk materials ahead of expensive downstream grinding and separation has many benefits including reduced energy and water usage, reduced operating costs and improved metal recoveries. Testing to assess sorting for a mineral deposit is normally conducted by the technology companies and there are no standard approaches to conducting such studies. The proposed study builds off of more than 20 years of research
experience to advance sensor based sorting.

Characterization and modification of a novel UVC-LED air disinfection chamber

With the recent COVID-19 pandemic and the quick disease transfer through airborne pathogens transmission specifically in the indoor environment, technologies such as UV-C air disinfection devices received significant attention. Industry rushed to market with a variety of solutions claiming to solve the issue and many of them already in question, leaving policy makers and the public confused. Therefore, more than ever, the public, policymakers and regulators are demanding science-backed data to validating the claims of commercially available technologies, including UV-C.

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