Mechanical locking and durability of engineered floor products

Despite the global growth of the flooring market and the need for more sustainable, efficient, and cost-effective flooring designs, there is little comparative information for the Canadian flooring industry to improve the design and fabrication of laminated floor panels to address both the mechanical performance and durability of their designs while manufacturing cost-effective products.

Deep Immunophenotyping of the Immune Response in Obstructive and Interstitial Lung Disease: Optimizing a Cellular and Protein Biomarker Discovery Pipeline for Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF), is a chronic debilitating lung disorder that affects thousands of Canadians and millions of individuals worldwide. The signs and symptoms of IPF often overlap with other common respiratory illnesses making a definitive diagnosis of this disease difficult. As a result, patients are frequently misdiagnosed and treated with inappropriate therapies. As such, there is a unmet clinical need to develop blood-based biomarkers for the confirmation of IPF to minimize the incidence of misdiagnosis.

Building Capacity for Campus Suicide Prevention: A Policy Practice Partnership

Post-secondary student mental health is of great concern, with increased rates of anxiety, depression, feelings of isolation, and suicidality observed. The COVID-19 pandemic has exacerbated mental health stressors and concerns about campus suicides, already on the rise. In response, the BC Ministry of Mental Health and Addictions has funded the BC Campus Suicide Prevention Initiative (CSPI), partnering with the Canadian Mental Health Association, BC division (CMHA BC) who will distribute funding and offer technical support to all 25 BC publicly funded post-secondary institutions.

Targeting a complement serine protease in vascular disease

In spite of major advances in our knowledge and better treatments, heart attacks, strokes and blood clots in the legs and lungs, continue to major causes of disability and death. Recent studies reveal that a protein (a so-called "serine protease") in our blood, when increased, may heighten the risk of excess blood clot formation in our blood vessels. Our studies are designed to determine how this protein works, and if by blocking its activity, we can prevent excess blood clotting. Our research program may uncover a more effective way to prevent blood vessel disease.

Improving reservoir shoreline erosion prediction methods: Lessons from the Site C headpond phase

The impoundment of a reservoir can cause erosion that poses risks to public safety and land use around its shoreline. Methods that are currently available to predict shoreline erosion rates and help manage these risks rely on inputs that are challenging to constrain without historical observations, resulting in uncertain predictions that may significantly underestimate or overestimate the risks.

Light-ends incorporation and new catalysts for hydroconversion of heavy oils

The proposed project seeks to improve the processing of Canadian oilsands bitumen using two key technical advancements associated with the upgrading of bitumen to fuels. Firstly, we will seek to reduce the consumption of costly hydrogen by using light-ends as a source of hydrogen and secondly we will improve the catalysts used to control the chemical reactions and thereby enhance liquid product yields.

Evaluating Attitudes Towards Needle Use, Experience with Needlestick Injuries, and the Uptake of a Needle-Safety Device Among Research Workers in British Columbia

Among healthcare workers the yearly global needlestick prevalence is 35.1%, which is expected to be much greater due to 30-50% needlesticks going unreported, putting a large number of workers at risk for contracting dangerous diseases and infections. However, data is lacking on how animal care and research personnel experience needlesticks compared to healthcare workers. Our study will investigate needle use and injuries in these neglected professions and determine underlying reasons that influence adherence to needle safety recommendations.

Development and preclinical evaluation of R-Sulforaphane-based therapeutics in treatment of chronic kidney disease

R-Sulforaphane (R-SFN) is a naturally occurring phytochemical that can be found in most of cruciferous vegetables, such as broccoli and kale. R-SFN has been shown in many research studies holding therapeutic promise for many chronic diseases. We propose to develop more advanced methodologies to product, purify and formulate R-SFN. We also propose to evaluate the therapeutic effect and safety profile of R-SFN in treating chronic kidney disease (CKD) in a rat model.

Microstructure Engineering of Aluminum Extrusions for the Automotive Sector

The use of aluminum alloys in automotive applications is increasing since the weight of the vehicle can be decreased. This is beneficial for both internal combustion and battery powered vehicles, to increase fuel economy and increase vehicle range, respectively. However, in general, aluminum alloys are more difficult to form and their performance during a vehicle crash may be challenging. Thus, it is necessary to understand the linkages between the production of the components and their performance. In many cases, components can be made by extrusion followed by heat treatment.

Smart Brush for Cattle

Cattle in commercial farming systems are highly motivated to use brushes to perform grooming and improve coat cleanliness. A change in brushing behavior may also serve as an early indicator of health and welfare problems. Farmers often provide rotating motorized brushes for cows but the currently available devices do not collect any data on which animal is using them and for how long, limiting the use of brushing behavior to inform management decisions.