In Vitro Screening and Validation of Phyto-Cannabinoids in Glaucoma

Glaucoma is the second leading cause of blindness in the world, mainly induced by increased pressure in the eye. Marijuana has been shown to reduce such pressure, thus benefit glaucoma patients. In this project, we test several components from marijuana extracts that are unlikely to cause psychoactive symptoms, for their therapeutic effects on glaucoma. This project is likely to be the solid base of a future drug that could help lots of glaucoma patients and meet the need of the market.

Kali: Optimizing Resource Utilization in Distributed Clusters

Decreasing operational costs is a key criterion for organizations that manage compute clusters, such as Amazon, Microsoft, Google, Alibaba, etc. One way to decrease costs it to improve resource utilization in the cluster [13, 14]. Yet, high resource utilization can negatively affect workload performance and thus user satisfaction. Performance degradation happens when workloads running on the same machine “compete” for shared resources, e.g., a workload that consumes a large portion of memory delays execution of other, memory-intensive workloads.

Development of transparent near-eye display using a sparse microlens array and lightfield principles

Head-mounted displays (HMDs) allow a convenient delivery of visualized data to the user. HMDs in the form of glasses and goggles (otherwise known as smart glasses and goggles), such as Vuzix Blade and Epson Moverio [1-3], have been introduced but the public acceptance of these devices have been rather lackluster. Part of the sluggish acceptance may be attributed to the still-high device costs (>$1000) and a large form-factor, owning largely to the fact that these devices utilize unique and sophisticated optics on dedicated and non-retrofittable platforms.

Exploring the use of physical modelling for assessing urban stream restoration design

Urban streams are prone to flooding and bank erosion as a result of the large amount of stormwater that is transported into the channel across the paved floodplain. Many streams in urban areas are being restored to a more natural state so that they are able to accommodate flood pulses as well as to increase habitat areas in and around the channel. Prior to the installation of restoration designs in urban areas, it is necessary to test that they will hold up under a range of flows and sedimentation.

The development of a novel oncolytic virotherapy for acute myeloid leukemia

Modern molecularly targeted therapies have shown promise in treating some blood cancers, but a cure remains elusive for most acute blood cancer patients. This is largely due to the survival of some blood cancer cells that possess unique properties and can cause treatment failure or relapse, highlighting the need for new therapies. In collaboration with Virogin Biotech Ltd, we aim to develop an innovative oncolytic virotherapy to effectively target acute myeloid leukemia (AML) patient cells that are resistant to current therapies.

Environmental productivity patterns of the Salish Sea: trends, impacts, projections

Pacific salmon are important from ecological, economic, social and cultural perspectives, but many species in the Salish Sea have seen drastic decrease in marine survival rate in recent decades, likely linked to reduced survival of the young stages of salmon due to a combination of environmental, food web changes, and human impacts. This activity will provide an ecosystem-level analysis of how the environmental productivity of the Salish Sea has changed in recent decades with focus on the implications this has had for salmon populations in the area.

Blockchain-based Consent Management for Personalized Medicine

This multidisciplinary project will investigate the social, data, and technical issues surrounding design and implementation of a blockchain-based solution for the management of consent for the use of individuals’ “omics” data in medical research. Blockchains are distributed ledgers in which confirmed and validated blocks are organized in an append-only chain using cryptographic links.

BC Pulp and Paper Bioproducts Alliance: Development and demonstration of forest residues to renewable natural gas technologies

This proposed project will support our ongoing efforts in scanning and screening existing technologies and de-bottlenecking key technology barriers in converting low-cost biomass residues to renewable natural gas in British Columbia pulp, paper and lumber mills. Specifically, we will focus on developing a bauxite residue (f.k.a., red mud) based catalyst for the removal of tar from gasification syngas to yield clean syngas for methanation to biomethane, and evaluating and improving the commercial methanation catalyst.

Level the field: sport and disability inclusion

UBC’s School of Kinesiology and viaSport British Columbia have received unding through the Social Sciences and Humanities Research Council (SSHRC) Partnership Development Grant program for a collaboration, titled Level the Field: Disability Inclusion in Sport. This work combines UBC’s research expertise and viaSport’s applied knowledge in an effort to understand how the sport sector can be made more inclusive for people with disabilities.

Identification of gene expression biomarkers for different biotic stress conditions in Arabidopsis thaliana and canola

Plants, like humans, sometimes get sick because of the activities of pathogens. When crops are diseased, their growth vigor will be severely damaged, leading to tremendous yield loss. To cure plant disease, farmers have been relying on synthetic pesticides for centuries; but the over-use of synthetic pesticides has caused pest resistance and serious environmental issues. To overcome this dilemma, companies like Terramera Inc. have been developing alternative powerful pest-managing products, namely biopesticides, which are eco-friendly bioactive agents derived from natural resources.