A novel scaffold for tympanic membrane repair

The ability to hear, and the quality of our hearing, depends on the health of the eardrum. Eardrum perforations due to diseases and accidents can be treated using grafts, such as autologous grafts, allografts and xenografts. These replacements suffer from various limitations such as donor site morbidity, long operation time and healing time, and risk of infection transmission, and more importantly, none of these grafts are able to replicate the complex microanatomy for sound quality reproduced by the native eardrum.

Valorizing Industrially Produced CO2: An Effective Solution for Carbon Capture and its Conversion to Marketable Products

Sequestering the industrially produced CO2 leads to its capture via the underground formation of stable inorganic carbonates/bicarbonates. An alternate approach is to convert the CO2 into valuable organic products having commercial markets. The incorporation of CO2 as block molecule with which to expand the platform is part of the Enerkem strategy aiming to further improve the use of Carbon from waste. Such strategy is deployable across Alberta.

Data-driven approach to establish a design space for raw materials properties and manufacturing conditions for pharmaceutical drug stability assurance

Pharmaceutical companies are required to perform stability testing of their drug products by regulation. A drug product that succeeds on stability testing means that its identity, potency, and purity remain within pre-established limits over its shelf life. Nowadays, drug products are more frequently reformulated in response to a highly competitive market, new research discoveries and the availability of new suppliers of raw materials.

Removal of Volatile Organic Compounds (VOCs) and Ozone (O3) from Gas Emissions

Volatile Organic Compounds (VOCs) generally refer to hydrocarbon solvents. VOCs emissions are air pollutants that give rise to deleterious health and environmental effects. VOCs are about 11 times more effective green house gases than carbon dioxide (CO2) (Reijo, 2010). VOCs react with oxides of nitrogen (NOx) to form Ozone (O3) which contributes to Green House Effect (GHE). Therefore, government has enforced regulations to limit the VOCs emissions. The target is to convert all VOCs (99%) to water and CO2 and Ozone (99%) to molecular dioxygen.

Développement de granulés combustibles d’origine agricole de qualité supérieure

Le secteur agricole québécois désire mettre en place une filière énergétique à la biomasse agricole. Toutefois, la combustion de biomasses agricoles en remplacement des combustibles fossiles rencontre certains freins à son développement. Comme la biomasse contient des quantités appréciables d’azote, de soufre, de chlore, de potassium et de silicium, sa combustion émet plus de particules et d’oxydes d’azote et de soufre et engendre davantage de problèmes d’opération (encrassement, corrosion et mâchefers).

Swiss-Roll Mixed Reactant Fuel Cell Chemistries

The project proposes to explore a series of alkaline chemistries in a novel Swiss-roll mixed reactant fuel cell (MRFC).The Swiss-roll MRFC is a recently developed fuel cell architecture which promises to significantly reduce the complexity and cost of scaling up fuel cell systems to commercially viable power supplies. The Swiss-roll MRFC concept has been proved with borohydride fuel, but as the borohydride system is limited in terms of commercial application, it is necessary to explore other fuels.

Metagenomic study of dechlorinating microbial communities invitro and in situ, part 2

The project is focused on study of commercial microbial cultures for biological remediation of soils and ground waters contaminated by chlorinated organic compounds. The successful elaboration and improvement of the products requires analysis on molecular-genetic level and detailed understating of organization of the microbial communities. The work benefits to industry partner by providing comprehensive information on functional and taxonomic structure, metabolic models of the studied microbial communities and key microorganisms involved in dechlorination of chloroform.

Development of a Solvent-Free Technology for Production of High Functional Protein Powders from Oilseeds and Grains

Oilseeds and grains are considered to be excellent sources of non-animal proteins containing the appropriate essential amino acids required for optimal human health. Conventional protein production methods involve the use of solvents, concentrated acids and alkali that result in protein denaturation, thereby reducing the quality and functionality of the protein ingredients. The proposed project will explore the potential of a dry or solvent free electrostatic-based separation technique for the production of high-quality protein powders from soy and navy beans.

Initial Investigation of the Synthesis andCharacterization of Novel Core-Shell Pt Catalysts

Presently, platinum (Pt) nanoparticles are required to catalyze the desired redox reactions at the anode and cathode of proton exchange membrane fuel cells (PEMFCs). The high cost of this precious metal catalyst remains a barrier to the wide spread commercialization of PEMFCs, particularly for automotive applications. In an effort to reduce the Pt loading in PEMFCs, this research project is focused on the design of novel catalysts which consist of depositing a 1-2 monolayer “shell” of Pt onto a less expensive metal which acts as a “core”.

Scale-up and Optimization of 3D Gel Dosimeters Year Two

The project aims at designing and manufacturing a series of products (gel dosimeters) that can be used for quality assurance of the radiation treatment of cancer: before treatment, a gel dosimeter is irradiated instead of the patient, and its colour changes to show the pattern of the delivered radiation dose. Then that colour change is imaged in a scanner and compared against the planned treatment. Any significant differences between the planned and delivered dose can be fixed before the patient is subjected to the radiation.