Rational programming of antigen structure using DNA nanotechnology to enhance vaccine immunogenicity

This project seeks to investigate how the nanoscale structure and arrangement of antigens influences immune recognition and vaccine efficacy. Using DNA nanotechnology and precise structural engineering, we aim to establish a structure-function paradigm linking antigen conformation and valency to immunogenicity. Using cancer vaccines as a stringent testbed of tumor antigens, the design rules established under […]

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Scalability Development of Fc3TSR Preparation Using Shake Flasks and Bioreactors

This project will help improve the way a promising new cancer treatment protein, called Fc3TSR, is made in the lab. Fc3TSR has shown the ability to shrink tumors by changing how blood vessels grow in cancer, making treatments like chemotherapy more effective. However, making enough of this protein for further testing and future use is […]

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Glycopolymer based Silicon Quantum Dots – Functionalization and Biological evaluation

Silicon quantum dots (SiQDs) are semiconductor nanoparticles with sizes ranging from 1 to 10 nm that show great promise for photonics, microelectronics, and fluorescent bio-imaging considering their ability to fluoresce from blue to near infrared light. In comparison to conventional quantum dots (which can release toxic metals), Si quantum dots are expected to be safer […]

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Electrohydrodynamics of Active Chiral Nematics

Our proposal investigates the electrohydrodynamics of active chiral nematics—complex fluids that combine internal activity, chirality, and orientational order. These materials exhibit rich flow behaviors and defect dynamics when subjected to electric fields, making them promising for future applications in soft robotics, microfluidics, and responsive materials. Through computational modeling and theoretical analysis, we aim to uncover […]

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AC Solar photovoltaic module testing for residential applications

The project’s purpose is to integrate Heliene’s solar photovoltaic (PV) panels with power electronics to create an integrated, high-performance solar module product for residential applications. The resulting AC solar module removes the need for external electronic components such as DC optimizers, inverters, diodes, and rapid shutdown devices. By integrating the external components, overall system reliability […]

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Scoliosis management through novel asymmetry surface topography analysis

Scoliosis is a condition where the spine curves abnormally, often developing in children and adolescents. To monitor how scoliosis progresses, patients usually have repeated x-rays over several years, sometimes as often as every six months. While this helps doctors track changes in the spine, it also means children are exposed to repeated radiation during an […]

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Pathfinder & AI Language Tutors: Smart Tools for Canadian PR Success

The proposed research project will focus on developing and improving an AI-powered tutoring app designed to help prospective immigrants enhance their language skills for permanent residency applications. Interns will refine the app’s features, including personalized lessons, real-time feedback, and exam simulations for IELTS and CELPIP. This project benefits the partner organization by offering an effective, […]

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Behaviour of post-installed adhesive anchors in concrete for crane-supporting structures

In steel structures, anchor bolts with steel base plates connect steel columns to concrete foundations. These anchors may experience different types of loading, including tension, shear, or combined shear and tension. There are two installation methods for anchors in reinforced concrete: cast-in-place anchors for new construction and post-installed anchors for existing structures. While research on […]

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Affordable Advanced Metering Technology Solutions (DERs for energy generation, distribution and consumption awareness with Real-time energy data)

iFormit Solutions Inc. develops accessible and cost-effective smart metering technologies aimed at improving transparency, accountability, and operational efficiency in utility consumption. Their solutions serve landlords, property managers, utility companies, and electric vehicle (EV) users who face challenges with the high cost and complexity of traditional smart metering systems. The core innovation, the iMID Connector, allows […]

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Advancing Sustainable Rammed Earth Construction: A Novel Robotics-Assisted Approach

This project tackles the lack of automation in sustainable construction practices, focusing specifically on rammed earth — an ancient technique now hindered by labor intensity and poor ergonomic conditions. Earth House Holdings, a BC-based ecological building firm, aims to introduce automation without compromising the low-carbon ethos of traditional earth construction. To address this, we propose […]

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