Preliminary work has shown that adding excess CEACAM1-specific antibody, 26H7, to hela cells expressing carcinoembryonic-antigen-related cell-adhesion moleule (CEACAM) 1-4L decreases CEACAM1-4L in the plasma membrane and shifts their surface expression from a monomer-oligomer mix to mainly monomers. A super resolution microscope will be used to co-localize CEACAM1-4L with 26H7 in order to determine the optimal […]
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