The human brain consists of more than 100 billion cells, many with specific structures and functions, performing complicated computations every day. Understanding these properties is a key component for the development of therapies for neurological disorders such as epilepsy, depression and brain tumours. So far, most of our knowledge of the human brain has been […]

Current therapies to manage pain either result in side effects or are insufficient and the associated medical costs and loss of work days come pose a tremendous socioeconomic burden. We recently showed that T-type channel activity is aberrantly regulated in inflammatory and neuropathic pain by the deubiquitinase USP5, and we have begun to explore this […]

We aim at developing new approaches which have not been performed so far, such as i) enhancing the resolution and quality of noisy and unlabeled conventional ultrasound images through deep learning SRMs, ii) synthesizing high-quality MRI from the enhanced ultrasound images through generative networks, iii) fusing ultrasound and synthetic MRI images for different aspects such […]

The milling oats in Canada are good sources of both dietary fibers and plant proteins. Currently the majority of Canadian oats is used as animal feed. Finding new sources of plant proteins and fibers or valorizing the existing ones is necessity to obtain sustainable and healthy food products. Even though oat lacks some essential amino […]

The aim of the EPES (Epilepsy Pre-Evaluation Space) is to create an immersive tool to better understand spatiotemporal phenomena inside epilepsy patients’ brains, by creating a 4D spatial-temporal visualization of electrical activity. Used for pre-surgical evaluation of epilepsy patients suited for surgical resection of the brain region, where seizures onset zone lies. EPES provides an […]

L’objectif de mon projet de recherche sera de faire ressortir les similitudes et les disparités concernant les recommandations de remboursements entre les agences d’évaluation des technologies de la santé au Canada (l‘INESSS pour le Québec et l’ACMTS pour l’ensemble des autres provinces) en fonction des différents champs thérapeutiques. Ce projet de recherche sera très pertinent […]

There is a pressing need for studies centered on the impact assessment of emerging wood preservatives and the remediation of orphaned sites. The present proposal describes a dual-purpose research project. The project aims to; (i) apply a modified in situ chemical oxidation technique for the removal of pentachlorophenol (Penta) and creosote compounds in orphaned sites […]

Biofilms are clusters of bacterial cells that grow together on a surface. Biofilms are often associated with infections (~65%) but they are exceedingly difficult to treat with conventional antibiotics and there are currently no biofilm-specific treatments available on the market. Some common biofilm-associated infections include skin and sinus infections as well as infections associated with […]

Mental illnesses, particularly depression, are one of the leading causes of global disease burden. In addition to reducing the quality of life of patients and their relatives, they costs billions of dollars annually to the Canadian economy. Unfortunately, current antidepressant drugs are barely satisfactory and have numerous side-effects. The goal of this project is to […]

The results obtained in this project will lead to new tools for the preparation of molecules of interest, possibly with biological activities. These studies will contribute to the development of new green synthetic methods using environmentally friendly catalysts. Efficient and practical synthetic methods are in high demand in the industrial and academic sectors. In particular, […]

Lesya Ukrainka Volyn National University has collected over 1000 narratives written by Ukrainian civilians about their experience of the ongoing Russia-Ukraine war. The objective of this research project is to use the narratives to discover commonalities in the language of the writers and to find whether there are linguistic markers of trauma across the narratives. […]

Half of all cancer patients receive radiotherapy, and of this group 15% will develop a tissue injury, or side effect, from the treatment. At present, however, there are no reliable methods for predicting a patient’s response to radiation therapy. We have studied mice with different genetic make ups and determined that there are certain genes […]