Exploring the commercial application of genetically engineered microalgae strains for the production of high valued metabolites for aquaculture fish feed

With the demand for high quality farmed fish on the rise, we are also expected to deliver on greater supplies of fish feed. Currently, fish feed is manufactured by capturing small foraging fish in the ocean, which are converted into pellets. This practice hinders marine life by disrupting the natural food chain of larger fish. […]

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Needs Assessment, Adaptation and Pilot Testing of a Patient Decision Aid for North American Elderly Women with Stress Urinary Incontinence

Effectuer une évaluation des besoins et élaborer un outil de prise de décision partagée comprenant des options de traitement conservateur et chirurgical pour aider les femmes de 60 ans et plus touchées par l’incontinence urinaire à l’effort. Notre étude contribuera à impliquer activement les femmes âgées dans les décisions concernant le traitement de leur incontinence […]

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Establishment, characterization, and directed differentiation of induced pluripotent stem cells for the improved treatment and understanding of pediatric brain tumors

Brain tumors occur in one out of each four children diagnosed with cancer. Sadly, these kids are less likely to survive their disease than those diagnosed with blood cancers. The kids that do survive brain cancer often suffer from side effects of treatment, which can hamper their ability to succeed later in life. Thus, the […]

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What can the oral microbiome tell us about child mental health?

There is a growing need to address the rising child mental health crisis in Canada. One way is to take a personalized medicine approach which includes factors that influence an individual’s environment, genetics and their microbiome. The microbiome includes a collection of microorganisms and can live on or within the human body. Many environmental factors […]

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Development of a Biocatalytic Process for the Endogenous Biogeneration of Functional Ingredients in Dairy Products: Lactosucrose, Kestose and Levan

Levansucrase (LS) is an enzyme that can catalyse reactions converting sugars, alkyl and phenolic compounds to complex oligosaccharides. In-depth studies are still needed regarding the reactions with alkyl and phenolic compounds which show high potential in increasing their antioxidant properties. In addition, further work is necessary to investigate the ability of LS to produce functional […]

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Effects of pain experience on fixed perceived effort motor tasks

Whilst, perceptions of effort have received increasing attention, the perception of pain has received much less attention despite its inherent role during voluntary activities such as exercise. Pain is defined as “an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage”. As such, pain is a regular […]

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Metabolic differences during metastasis of epithelial ovarian cancers

Epithelial ovarian cancer (EOC) is a debilitating disease that has a 5-year survival rate of only 44%, making it the fifth most lethal cancer in women. A major reason for this low survival rate is the high rate of metastasis, where cells detach from the primary tumour site on the ovary and reattach at secondary […]

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Investigating AKT1-dependent pathways to regulate cellular metabolism

The serine/threonine kinase AKT1 is a key mediator of cell growth and survival processes including glucose metabolism, apoptosis, transcription, proliferation, and migration. AKT1 is activated by phosphorylation at two key regulatory sites, Threonine308 and Serine473, that are both used as clinical diagnostic markers for cancer. AKT1 also plays an important role in glucose metabolism by […]

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Extrusion printing of hydrogels for cell therapies

Hydrogels have been widely researched as biomaterials for cell and drug delivery. Allarta has developed polymer-based capsules, based on pioneering research at McMaster University, with a range of diffusion profiles. Allarta has shown the ability of these hydrogels to support different mammalian cell types including stem cells and islets. Furthermore, such cell-containing hydrogels have been […]

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Développement d’une écloserie de homard aux Îles-de-la-Madeleine

La pêche au homard américain est un des principaux moteurs économiques aux Îles-de-la-madeleine. En 2021, les débarquements de ce crustacé ont représenté plus de 60% du total des captures effectuées toutes espèces confondues. Bien que ces chiffres soient plus qu’encourageants pour l’industrie des pêches ainsi que l’économie madelinienne, il convient de demeurer prudent en considérant […]

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Development and evaluation of WinSport’s IPLAY program: A mixed methods examination of a physical literacy-based initiative for newcomer youths

Physical literacy (PL) programs focus on developing competence, confidence, and the knowledge to be physically active (PA) across the lifespan. Given that current rates of PA among children are continuing to decline, with only 9% of children meeting the Canadian PA guidelines, PL programs provide a unique opportunity to facilitate a lifelong interest in PA. […]

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