Le contrôle moteur étudié chez le rongeur par une analyse cinématique 3D

Nous étudions les mécanismes de la récuperation motrice chez le rongeur, où nous développons des systèmes intégrés d’intervention par neuromodulation du cerveau et de la moelle épinière. M. Ferotin mettra en œuvre un pipeline d’analyse cinématique 3D basé sur trois caméras positionnées autour d’une plate-forme comportementale, où le contrôle du mouvement des membres antérieurs du […]

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Development and manufacturing of functionalized oxime crosslinked hyaluronan hydrogel for sustained drug release to treat retinal degeneration

Retinal degeneration disorders are among the leading causes of blindness in the developed world. Several therapies hold promise, however widespread application is hindered due to difficulty in delivering active drug to the retina. Synakis is a company that has developed a biomaterial that can be injected into the eye to aid in retinal surgeries. This […]

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Developing chemical probes for inhibition and targeted degradation of the deubiquitinase USP9X in breast cancer

Cells have developed an intricate system called ubiquitination to control the quantity of certain proteins. As this is frequently hijacked in various cancers, the Structural Genomics Consortium (SGC) intends to inhibit components of ubiquitination with small molecules for therapeutic benefit. Partnership of the SGC with the cell biology expertise of Barsyte-Lovejoy group will allow for […]

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Is correction of malnutrition sufficient to improve low physical function before elective colorectal cancer surgery? A randomized controlled trial of nutrition vs nutrition and exercise prehabilitation

Bowel cancers and diseases are treated with surgery. But recovery from surgery is difficult. Patients can experience long hospital stays, complications after surgery, and a delay in the return of their usual daily activities. The 6-min walk distance (6MWD) is a test performed before surgery to evaluate physical fitness. If a patient is unable to […]

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Effectiveness of Vibration Massage in Automotive Seating

This research study will examine the effectiveness of a vibration massage system in automotive seating. The vibration parameters of the massage system will be tested by examining different vibration frequencies, types of vibration exposure, and location of the vibration while occupants are sitting in an automotive seat. The intern will measure biometric data of the […]

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Compliance and effectiveness monitoring of stream barrier remediations on salmonid bearing streams in British Columbia

Over 400,000 culvert stream crossings are present in British Columbia, with many acting as barriers to fish passage. The frequency of culverts on the landscape has made them the leading cause of linear stream habitat fragmentation for salmonids and a restoration priority. Fisheries and Oceans Canada (DFO), the British Columbia Fish Passage Technical Working Group […]

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Evaluation of phytochemicals bioavailability and antioxidant capacity in South African common indigenous foods

Phytochemicals are secondary metabolites that offer biological activity to prevent degeneration of different non-communicable diseases such as type-2 diabetes (Stroke), cardiovascular disease, and cancer. Indigenous food crops are rich source of phytochemicals such as phenolic acids and flavonoids which have demonstrated some biological activities including antioxidant, anti-inflammation and anti-bacterial effect. This study aims to screen […]

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From ‘salmon management’ to ‘salmon caretaking’: a collaborative, two-eyed seeing, rights-based approach to salmon conservation

Via a collaborative research project with the Dandzen Development Ltd. Partnership, we seek to improve conservation of ts’emen (sockeye) and jâs (Chinook) salmon along the Fraser and Chilko Rivers. The Gwets’en Nilt’i Pathway Agreement between the T?ilhqot’in Nations, the Government of Canada, and the Government of BC only considers the input from the T?ilhqot’in on […]

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The use of IoT and big data by public and global health agencies to quantify the outcomes and adverse health impacts of air pollution

Air pollution is a global public health concern. It is responsible for a cascade of adverse health outcomes. However, quantifying the outcomes and impacts of air pollution is difficult. The advancement of IoT and big data technologies can now allow public health officials and researchers to monitor air pollution levels and take appropriate and rapid […]

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A four dimensional neurodevelopmental atlas of the mouse brain

Surgical manipulation (e.g., injections, electrode placement) in the developing mouse brain is essential for neuroscientists in order to study the structure and function of the brain and behaviour. Unfortunately, most atlases used in targeting are based on static adult mouse anatomical brain features. Here we propose the use of 4-dimentional (4D) brain atlases (time being […]

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