Our goal is to employ a host of new compounds, made by the applicant in her lab in Brazil, for drug discovery studies at the University of Toronto. Specifically, the host uses a technique called Nuclear Magnetic Resonance (NMR) to obtain signatures of drugs or ligands. These signatures can identify those compounds which bind strongly […]

Helicobacter pylori (HP) colonizes chronically ~50% of the world’s population, causing gastric tissue inflammation and gastric ulcers or cancers. Lactic Acid Bacteria (LAB) have probiotic effects against HP, meaning that they help alleviate symptoms. We found that 5 LAB provided by partner Lallemand Health Solutions (LHS) produce and release molecules that inhibit the growth of […]

The aim of this project is to assess the long-term impacts of transport poverty in Canada using mixed methods approach. Transport poverty is the combined effect of transport disadvantage (including but not limited to inadequate public transport options, poor public transport accessibility, not owning or having access to car, perception of safety) and various socio- […]

Aim of the study: The aim of this study is to compare the SARS-CoV-2 sequencing data available from the north American/Canadian SARS-CoV-2 outbreaks in mink to the Danish SARS-CoV-2 outbreaks in mink, and compare genetic similarities. Moreover, a secondary aim is to investigate the antibody response in relation to SARS-CoV-2 outbreak in Canadian mink to […]

Since 2000, interior Fraser River steelhead (IFRS) have declined to historic low abundance. Due to this, COSEWIC in 2018 designated IFRS as endangered. Hatchery propagation can reduce interannual variability in egg-to-fry survival rates and increase the freshwater abundance of juveniles. There remains controversy over the effectiveness of hatchery operation as a conservation measure. Some studies […]

Glaucoma and cataracts are separate, but serious conditions of the eyes. If not properly managed, both can lead to significant vision loss. Currently, there is limited quality monitoring of vision care across the Alberta. The standardized use of performance measures that evaluate the glaucoma and cataract care is paramount to improving the quality of vision […]

Amplitude Ventures mission is centered around creating, growing and accelerating companies based on Canadian innovative research. Our goal with this project is to continue developing our company creation process. We will identify innovative scientific concepts that have the potential to evolve into IP and constitute a company in the future with the goal of designing […]

Plants are fundamental to the survival of humankind. They create the oxygen we breathe, provide the food we consume, and supply raw materials for numerous industries. We want to know how plants cope with stress. This requires a deep understanding of how plant tissues and cells react to stress cues, which includes understanding how proteins […]

Asbestos was once used extensively in the fabrication of a variety of products and materials. After being declared a carcinogen and linked with a variety of lung diseases more than 2 decades ago, the use of asbestos was banned in many countries. Yet, asbestos remains a public health concern worldwide and one of the leading […]

Those living with homelessness and in precarious housing situations experience several barriers to accessing psychological care despite often needing support for their mental health. Some of these barriers include lack of funding to pay for services and difficulty physically accessing services. Providing mental health care virtually, can reduce these barriers by making services more accessible […]

A human protein “interleukin-2” plays a key role in immunity. The target of this project is to modify this protein, triggering more immune cells in body, and hence enhancing body defense. At first, the intern will produce normal interleukin-2 in bacteria. The protein will then be mixed with the immune cells. Increase in cell amount […]

There remains a high incidence of foodborne illness and product recalls due to contamination such as Listeria. Salmonella and E. coli. Although a range of synthetic preservatives are available there is a preference for natural antimicrobial agents such as protective cultures. In the proposed research a novel combination of lactic acid bacteria developed by Biointeligenza […]